年龄相关功能性听力下降对记忆功能的影响

doi:10.3969/j.issn.1006-9771.2020.09.017

《中国康复理论与实践》 ›› 2020, Vol. 26 ›› Issue (9): 1093-1096.doi: 10.3969/j.issn.1006-9771.2020.09.017

年龄相关功能性听力下降对记忆功能的影响

王贞¹,张庆苏¹,胡乃晓¹,王琦¹,龚树生²()

1.中国康复研究中心北京博爱医院听力语言科,北京市 100068
2.首都医科大学北京友谊医院耳鼻喉头颈外科,北京市 100050

收稿日期:2019-08-27 修回日期:2020-02-13 出版日期:2020-09-25 发布日期:2020-09-24
通讯作者: 龚树生 E-mail:gongss1962@163.com
作者简介:王贞(1979-),女,汉族,河北文安县人,硕士研究生,主治医师,主要研究方向：听力语言障碍的康复治疗。|龚树生(1962-),男,湖北赤壁市人,博士,教授、主任医师,主要研究方向：耳科学临床及基础研究。
基金资助:
中央级公益性科研院所基本科研业务费专项基金项目(2015CZ-35)

Influence of Age-related Functional Hearing Loss on Memory

WANG Zhen¹,ZHANG Qing-su¹,HU Nai-xiao¹,WANG Qi¹,GONG Shu-sheng²()

1. Department of Speech and Hearing Therapy, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
2. Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

Received:2019-08-27 Revised:2020-02-13 Published:2020-09-25 Online:2020-09-24
Contact: GONG Shu-sheng E-mail:gongss1962@163.com
Supported by:
National Special Fund Projects of Basic Research of Public Benefits for Institutes at Central Governmental Level(2015CZ-35)

摘要/Abstract

摘要：

目的研究年龄相关功能性听力损失对记忆功能的影响。
方法 2018年1月至10月,耳鼻喉科门诊中老年患者30例(年龄52~76岁),根据测听结果,噪声下言语识别能力好的(SIN < -2.63 dB)入L组( n = 15),识别能力差的(SIN > -2.63 dB)入H组( n = 15)。采用剑桥神经心理学成套测试(CANTAB)中4、6、8个模型负荷的配对联结学习(PAL)和空间工作记忆(SWM)进行评定。
结果两组PAL和SWM错误数均随负荷上升而显著上升(χ²> 28.182,P < 0.001)。不同负荷下,L组PAL错误数均低于H组( U < 53.5, P < 0.05);6个模型负荷下,L组SWM错误数低于H组( U = 55.0, P < 0.05)。听力与负荷交互效应不显著( F < 1.680, P > 0.05)。
结论年龄相关功能性听力下降对情景记忆的影响较工作记忆更多,与记忆负荷无关。

关键词: 功能性听力下降, 年龄, 工作记忆, 情景记忆, 记忆负荷

Abstract:

Objective To study the influence of age-related functional hearing loss on memory ability.
Methods From January to October, 2018, 30 patients aged 52 to 76 years visiting otolaryngology were screened hearing using a computer aided platform, and then were divided into two groups according to the results. Those with good speech recognition in noise (SIN < -2.63 dB) were in L group ( n = 15) and those with poor speech recognition in noise (SIN > -2.63 db) were in H group ( n = 15). They were assessed with Paired Associates Learning (PAL) and Spatial Working Memory (SWM) of Cambridge Neuropsychological Test Automated Battery in loading of four, six and eight models.
Results The amount of errors of both PAL and SWM increased with the loading in both groups (χ²> 28.182,P < 0.001). The amount of errors of PAL was less in L group than in H group under any loading ( U < 53.5, P < 0.05), while the amount of errors of SWM only less under loading of six models ( U = 55.0, P < 0.05). There was no significant interaction between hearing and loading ( F < 1.680, P > 0.05).
Conclusion Age-related functional hearing loss tend to impair episodic memory rather than working memory, whatever the impacts of memory load.

Key words: functional hearing loss, age, working memory, episodic memory, memory load

王贞,张庆苏,胡乃晓,王琦,龚树生. 年龄相关功能性听力下降对记忆功能的影响[J]. 《中国康复理论与实践》, 2020, 26(9): 1093-1096.

WANG Zhen,ZHANG Qing-su,HU Nai-xiao,WANG Qi,GONG Shu-sheng. Influence of Age-related Functional Hearing Loss on Memory[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(9): 1093-1096.

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参考文献 19

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组别	n	性别(n)		年龄(岁)	教育程度(年)	SIN(dB)
组别	n	男	女	年龄(岁)	教育程度(年)	SIN(dB)
L组	15	6	9	63.60±5.92	11.40±3.18	8
H组	15	9	6	67.00±7.76	13.07±3.17	23
χ²/t/U值				1.349	1.321	0.000
P值		1.000		0.216	0.433	< 0.001

组别	任务	4	6	8	χ²值	P值	M₁值	P₁值	M₂值	P₂值	M₃值	P₃值
L组	PAL	0.00(0.00~1.10)	2.08(1.79~2.20)	3.00(2.83~3.09)	30.000	< 0.001	-2.739	0.019	-5.477	< 0.001	-2.739	0.019
	SWM	0.00(0.00~0.69)	1.39(0.69~1.79)	2.20(1.79~2.64)	28.182	< 0.001	-1.826	0.204	-5.021	< 0.001	-3.195	0.004
H组	PAL	1.10(0.69~1.61)	2.30(2.08~2.40)	3.21(3.10~3.37)	30.000	< 0.001	-2.739	0.019	-5.477	< 0.001	-2.739	0.019
	SWM	0.69(0.00~1.10)	1.95(1.61~2.20)	2.56(2.30~2.64)	29.525	< 0.001	-2.556	0.032	-2.830	0.014	-5.386	< 0.001
	U_a值	53.5	51.0	33.0
	P_a值	0.013	0.010	0.001
	U_a值	99.0	55.0	70.5
	P_a值	0.595	0.016	0.081

组别	PAL4	PAL6	PAL8	SWM4	SWM6	SWM8
L组	0.378±0.148	1.940±0.084	2.878±0.106	0.397±0.140	1.268±0.199	2.154±0.134
H组	1.041±0.177	2.262±0.080	3.218±0.037	0.524±0.149	1.888±0.120	2.487±0.062

年龄相关功能性听力下降对记忆功能的影响

Influence of Age-related Functional Hearing Loss on Memory

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