《中国康复理论与实践》 ›› 2020, Vol. 26 ›› Issue (11): 1287-1291.doi: 10.3969/j.issn.1006-9771.2020.11.007
收稿日期:
2020-01-21
修回日期:
2020-02-17
出版日期:
2020-11-25
发布日期:
2020-11-24
通讯作者:
陈柱
E-mail:812885660@qq.com
作者简介:
陈柱(1990-),女,汉族,江苏海安市人,硕士,主管技师,主要研究方向:脑损伤后语言、认知及吞咽功能的康复。
基金资助:
CHEN Zhu1,2(),LU Yao1,CHEN Yi-yi1
Received:
2020-01-21
Revised:
2020-02-17
Published:
2020-11-25
Online:
2020-11-24
Contact:
CHEN Zhu
E-mail:812885660@qq.com
Supported by:
摘要:
神经调控技术基于皮质修复机制,通过电或化学方法直接或间接作用于大脑皮质,影响神经元兴奋性,辅助神经网络重建,促进功能恢复。经颅直流电刺激和经颅磁刺激技术近年来在吞咽障碍康复中被广泛应用,且疗效显著。吞咽障碍患者可根据大脑皮质受损情况,选择适宜的恢复模型,通过电极部位、频率的选择,实施不同的神经调控干预策略,兴奋、抑制或调控大脑目标皮质,从而改善吞咽功能。
中图分类号:
陈柱,陆瑶,陈宜懿. 神经调控技术在吞咽障碍康复中的应用进展[J]. 《中国康复理论与实践》, 2020, 26(11): 1287-1291.
CHEN Zhu,LU Yao,CHEN Yi-yi. Application of Neuromodulation in Rehabilitation for Dysphagia (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(11): 1287-1291.
表1
rTMS刺激吞咽皮质改善患者吞咽功能的相关研究"
研究者 | 刺激方式 | 效果 | 参考策略 |
---|---|---|---|
Verin等[ | 刺激吞咽皮质 | 吞咽功能改善 | rTMS真刺激 |
进食时吞咽反应更快 | |||
Khedr等[ | 刺激受损皮质 | 真刺激有效 | rTMS真刺激 |
伪刺激组治疗2个月也未见吞咽功能显著改善 | |||
郑秀琴等[ | 以1 Hz、5 Hz和10 Hz刺激健康成人 | 5 Hz的刺激对吞咽皮质既有兴奋作用,也有后续效应 | 高频rTMS (5 Hz) |
1 Hz和10 Hz rTMS均无兴奋效应 | |||
Khedr等[ | 3 Hz刺激受损侧皮质 | 吞咽功能较前改善 | 高频rTMS (3 Hz) |
吞咽肌肉运动诱发电位振幅较前增大 | |||
Park等[ | 5 Hz刺激健侧咽部皮质区 | 健侧皮质兴奋性增加 | 高频rTMS (5 Hz) |
延髓运动神经元兴奋性增加 | |||
投射到咽部的刺激增加 | |||
Verin等[ | 1 Hz刺激吞咽障碍患者健侧皮质 | 患者吞咽协调性提高 | 低频rTMS (1 Hz) |
Du等[ | 以1 Hz和3 Hz刺激吞咽障碍患者皮质 | 1 Hz降低健侧皮质兴奋性,增加患侧皮质兴奋性 | 低频rTMS (1 Hz) |
3 Hz增强患侧皮质兴奋性 | |||
焦勇钢等[ | 3 Hz刺激急性期患者双侧相应区域 | 双侧高频刺激效果优于单侧刺激 | 双侧高频rTMS (3 Hz) |
Khedr等[ | 3 Hz刺激双侧吞咽运动区大脑皮质 | 治疗延髓损伤吞咽困难有效 | 双侧高频rTMS (3 Hz) |
可提高皮质延髓的兴奋性 |
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