电针促进经颅磁刺激治疗意识障碍效果的失匹配负波观察

doi:10.3969/j.issn.1006-9771.2021.01.015

《中国康复理论与实践》 ›› 2021, Vol. 27 ›› Issue (1): 102-106.doi: 10.3969/j.issn.1006-9771.2021.01.015

电针促进经颅磁刺激治疗意识障碍效果的失匹配负波观察

陈喆思¹, 刘建成¹, 赵小华¹, 郑重², 柏玲¹, 杨丹¹, 王文春¹

1.西部战区总医院，四川成都市 610083
2.四川大学华西医院，四川成都市 610041

收稿日期:2019-11-13 修回日期:2020-02-07 出版日期:2021-01-25 发布日期:2021-01-27
通讯作者: 王文春，E-mail： 852900340@qq.com
作者简介:陈喆思(1984-)，男，汉族，四川成都市人，硕士，主治医师，主要研究方向：神经电生理、针灸；王文春，男，硕士，副主任医师。
基金资助:
四川省卫生健康委员会基金项目(No. 19PJ158)

Effects of Electroacupuncture on Consciousness Disorders Based on Transcranial Magnetic Stimulation: Study with Mismatch Negativity

CHEN Zhe-si¹, LIU Jian-cheng¹, ZHAO Xiao-hua¹, ZHENG Zhong², BAI Ling¹, YANG Dan¹, WANG Wen-chun¹

1. The General Hospital of Western Theater Command, Chengdu, Sichuan 610083, China
2. West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

Received:2019-11-13 Revised:2020-02-07 Published:2021-01-25 Online:2021-01-27
Contact: WANG Wen-chun, E-mail: 852900340@qq.com
Supported by:
Sichuan Healthy Committee Foundation (No. 19PJ158)

摘要/Abstract

摘要： 目的观察在经颅磁刺激(TMS)的基础上结合电针在促醒方面的疗效。方法 2015年1月至2019年10月，西部战区总医院收治的意识障碍住院患者30例，随机分为对照组(n = 15)和观察组(n = 15)。对照组行TMS治疗，观察组另行电针百会、神庭、双侧内关、双侧合谷、双侧涌泉穴，共3个月。治疗前、治疗1个月、治疗3个月后检测失匹配负波(MMN)，采用格拉斯哥昏迷量表(GCS)、持续植物状态(PVS)评分进行评定。结果治疗3个月后，观察组MMN潜伏期较对照组缩短(t = 2.159, P < 0.05)。结论电针可加强TMS的促醒效果。

关键词: 意识障碍, 电针, 经颅磁刺激, 促醒, 失匹配负波

Abstract: Objective To observe the effect of electroacupuncture based on transcranial magnetic stimulation (TMS) on wakefulness for consciousness disorder. Methods From January, 2015 to October, 2019, 30 inpatients with consciousness disorder from the General Hospital of Western Theater Command were randomly divided into control group (n = 15) and observetion group (n = 15), Both groups received TMS, and the observetion group received electroacupuncture at Baihui (GV20), Shenting (GV24), bilateral Neiguan (PC6) bilateral Hegu (LI4) and bilateral Yongquan (KI1) in addition, for three months. They were tested the latency of the mismatch negativity (MMN), and assessed with Glasgow Coma Scale (GCS) and persistent vegetative state (PVS) score before, and one month and three months after treatment. Results The latency of MMN decreased more in the observetion group than in the control group three months after treatment (t = 2.159, P < 0.05). Conclusion Combination of electroacupuncture on TMS is more effective on wakefulness for consciousness disorder.

Key words: consciousness disorder, electroacupuncture, transcranial magnetic stimulation, wakefulness, mismatch negativity

中图分类号:

R742

陈喆思, 刘建成, 赵小华, 郑重, 柏玲, 杨丹, 王文春. 电针促进经颅磁刺激治疗意识障碍效果的失匹配负波观察[J]. 《中国康复理论与实践》, 2021, 27(1): 102-106.

CHEN Zhe-si, LIU Jian-cheng, ZHAO Xiao-hua, ZHENG Zhong, BAI Ling, YANG Dan, WANG Wen-chun. Effects of Electroacupuncture on Consciousness Disorders Based on Transcranial Magnetic Stimulation: Study with Mismatch Negativity[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2021, 27(1): 102-106.

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电针促进经颅磁刺激治疗意识障碍效果的失匹配负波观察

Effects of Electroacupuncture on Consciousness Disorders Based on Transcranial Magnetic Stimulation: Study with Mismatch Negativity

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