《中国康复理论与实践》 ›› 2022, Vol. 28 ›› Issue (5): 502-507.doi: 10.3969/j.issn.1006-9771.2022.05.002
曹志刚,冯海霞(),李亚斌,杨佳丽,李姣,王红霞,曲博轩,张亚云
收稿日期:
2022-03-28
修回日期:
2022-05-19
出版日期:
2022-05-25
发布日期:
2022-06-10
通讯作者:
冯海霞
E-mail:2081676403@qq.com
作者简介:
曹志刚(1994-),男,汉族,甘肃兰州市人,初级治疗师,主要研究方向:神经康复。
基金资助:
CAO Zhigang,FENG Haixia(),LI Yabin,YANG Jiali,LI Jiao,WANG Hongxia,QU Boxuan,ZHANG Yayun
Received:
2022-03-28
Revised:
2022-05-19
Published:
2022-05-25
Online:
2022-06-10
Contact:
FENG Haixia
E-mail:2081676403@qq.com
Supported by:
摘要:
目的 探讨脑卒中后多靶区大脑皮质间歇性θ爆发式磁刺激(iTBS)对偏瘫侧上肢功能恢复的影响。方法 2019年11月至2020年8月,甘肃省康复中心医院40例脑卒中患者随机分为单靶区刺激组(n = 20)和多靶区刺激组(n = 20)。两组均进行临床常规药物治疗和日常康复锻炼。在此基础上,两组均辅以重复经颅磁刺激(iTBS模式)。单靶区刺激组仅刺激患侧脑部初级运动皮质(M1区);多靶区刺激组先刺激健侧大脑同侧小脑半球皮质,5 s后再刺激患侧大脑M1区。每天1次,每周6 d,共4周。治疗前和治疗4周后比较两组Fugl-Meyer评定量表-上肢部分(FMA-UE)、上肢动作研究量表(ARAT)、改良Barthel指数(MBI)评分以及上肢体感诱发电位N20 (潜伏期、波幅)的变化。结果 所有患者均无不良反应发生。治疗后,两组FMA-UE、MBI和ARAT评分,N20潜伏期和波幅均改善(|t| > 3.478, |Z| > 2.243, P < 0.05),且多靶区刺激组FMA-UE和ARAT评分,N20波幅均明显优于单靶区刺激组(t > 2.939, Z = -2.697, P < 0.01)。结论 多靶区刺激比单靶区刺激更能改善脑卒中患者偏瘫侧上肢运动功能和患侧N20波幅。
中图分类号:
曹志刚,冯海霞,李亚斌,杨佳丽,李姣,王红霞,曲博轩,张亚云. 基于大脑半球之间多靶区间歇性θ爆发式磁刺激对脑卒中患者上肢功能的影响[J]. 《中国康复理论与实践》, 2022, 28(5): 502-507.
CAO Zhigang,FENG Haixia,LI Yabin,YANG Jiali,LI Jiao,WANG Hongxia,QU Boxuan,ZHANG Yayun. Effects of interhemispheric multi-target intermittent theta burst stimulation on upper limb function in patients with stroke[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(5): 502-507.
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