《中国康复理论与实践》

《中国康复理论与实践》 ›› 2023, Vol. 29 ›› Issue (10): 1135-1139.doi: 10.3969/j.issn.1006-9771.2023.10.003

• 专题 身体活动与健康 • 上一篇    下一篇

体力活动水平对帕金森病发病风险的影响：基于CHARLS数据的横断面分析

吴佳玉1, 孟德涛2, 梁潇潇1()   

  1. 1.厦门弘爱康复医院神经康复科，福建厦门市 361000
    2.首都医科大学附属北京康复医院帕金森医学中心，北京市 100144
  • 收稿日期:2023-06-15 修回日期:2023-09-11 出版日期:2023-10-25 发布日期:2023-11-16
  • 通讯作者: 梁潇潇(1972-)，女，硕士，主任医师，主要研究方向：帕金森病、神经康复。E-mail： 13464855968@163.com
  • 作者简介:吴佳玉(1989-)，女，汉族，福建厦门市人，硕士研究生，主治医师，主要研究方向：帕金森病、神经康复。
  • 基金资助:
    厦门市医疗卫生指导性项目(3502Z20224ZD1359)

Effect of physical activity levels on risk of Parkinson's disease: a cross-sectional analysis based on China Health and Retirement Longitudinal Study

WU Jiayu1, MENG Detao2, LIANG Xiaoxiao1()   

  1. 1. Department of Neurorehabilitation, Xiamen Humanity Rehabilitation Hospital, Xiamen, Fujian 361000, China
    2. Parkinson's Medical Center, Beijing Rehabilitation Hospital Affiliated to Capital Medical University, Beijing 100144, China
  • Received:2023-06-15 Revised:2023-09-11 Published:2023-10-25 Online:2023-11-16
  • Contact: LIANG Xiaoxiao, E-mail: 13464855968@163.com
  • Supported by:
    Xiamen Medical and Health Guidance Project(3502Z20224ZD1359)

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摘要：

目的 探讨不同程度体力活动水平对帕金森病发病的影响。
方法 采用2018年中国健康与养老追踪调查(CHARLS)数据，对9 726例受试者的自我报告数据进行多因素Logistic回归分析。
结果 9 726例受试者中，188例患有帕金森病，患病率为1.93%。年龄≥ 65岁(OR = 2.58, 95%CI 1.74~3.96, P < 0.001)、丧偶(OR = 1.42, 95%CI 1.01~1.99, P = 0.043)的受试者患帕金森病的风险较高，高强度体力活动(> 3 000 代谢当量/周)(OR = 0.38, 95%CI 0.27~0.54, P < 0.001)受试者患帕金森病的风险较低。在调整年龄、婚姻状态后，高强度体力活动仍可降低帕金森病的发病风险(OR = 0.42, 95%CI 0.29~0.61, P < 0.001)。
结论 高强度体力活动可能会降低帕金森病的发病风险。

关键词: 帕金森病, 中年人, 老年人, 风险, 体力活动

Abstract:

Objective To investigate the effect of different levels of physical activity on the risk of Parkinson's disease (PD).
Methods A total of 9 726 subjects from 2018 China Health and Retirement Longitudinal Study (CHARLS) data were analyzed with multivariate Logistic regression analysis.
Results Of the 9 726 subjects, 188 suffered from PD, with a prevalence of 1.93%. The subjects who aged more than 65 (OR = 2.58, 95%CI 1.74 to 3.96, P < 0.001) and widowed (OR = 1.42, 95%CI 1.01 to 1.99, P = 0.043) were at a higher risk of developing PD. Subjects who engaged in high-intensity physical activities (OR = 0.38, 95%CI 0.27 to 0.54, P < 0.001) were at a lower risk of PD. After adjusting for age and marital status, high-intensity physical activity still reduced the risk of PD (OR = 0.42, 95%CI 0.29 to 0.61, P < 0.001).
Conclusion High-intensity physical activity (over 3 000 metabolic equivalents a week) may reduce the risk of PD.

Key words: Parkinson's disease, middle-aged, elderly, risk, physical activity

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