《中国康复理论与实践》 ›› 2024, Vol. 30 ›› Issue (3): 316-325.doi: 10.3969/j.issn.1006-9771.2024.03.009
收稿日期:
2024-02-06
出版日期:
2024-03-25
发布日期:
2024-04-01
通讯作者:
常静玲
E-mail:ear6979@163.com
作者简介:
黄幸(1991-),女,汉族,湖南邵东市人,博士研究生,主治医师,主要研究方向:中医药防治脑病的临床与神经电生理(脑电)研究。基金资助:
HUANG Xing1,2, CHANG Jingling1(), ZHANG Zihan1, LI Ying1
Received:
2024-02-06
Published:
2024-03-25
Online:
2024-04-01
Contact:
CHANG Jingling
E-mail:ear6979@163.com
Supported by:
摘要:
目的 探索卒中后失语(PSA)工作记忆的任务态脑电特征。
方法 2020年9月至2021年2月,于北京中医药大学东直门医院招募PSA患者(PSA组)和健康受试者(HC组)各8例,采集脑电图和记忆量表数据,通过工作记忆任务态的脑电数据分析时域事件相关电位(ERP)和时频的脑电频段指标特点,与记忆量表中的各项目进行相关性分析。
结果 最终纳入10例,每组5例。ERP分析发现前额区诱发N1和P2成分,顶枕区诱发P300成分。与HC组相比,PSA组在出现条件下,中央前额区N1和P2激活增强,右侧顶枕区P300活动降低(|t| > 2.193, P < 0.05)。与HC组相比,PSA组在未出现条件下右侧前额区、中央顶枕区θ频段能量降低,左侧顶枕区α1频段能量降低,左侧中央区γ频段能量增加(t > 2.398, P < 0.05)。相关性分析显示,γ频段的能量与听觉词语学习测验中的即刻回忆(r = 0.914, P = 0.030)、正确再认(r = 0.931, P = 0.022)和数字广度测验中的倒背(r = 0.924, P = 0.025)、顺背(r = 0.889, P = 0.044)呈强正相关。
结论 视觉工作记忆任务可调动PSA患者记忆相关脑区代偿活动,可作为PSA工作记忆相关研究的评价客观指征。语言损伤与工作记忆之间存在密切联系。
中图分类号:
黄幸, 常静玲, 张梓寒, 李颖. 卒中后失语工作记忆的事件相关电位及时频特征[J]. 《中国康复理论与实践》, 2024, 30(3): 316-325.
HUANG Xing, CHANG Jingling, ZHANG Zihan, LI Ying. Characteristics of event-related potential and frequency on working memory of post-stroke aphasia[J]. Chinese Journal of Rehabilitation Theory and Practice, 2024, 30(3): 316-325.
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