《中国康复理论与实践》 ›› 2025, Vol. 31 ›› Issue (2): 231-234.doi: 10.3969/j.issn.1006-9771.2025.02.013

• 应用研究 • 上一篇    下一篇

膀胱变形指数对神经源性膀胱患者上尿路损伤的预测价值

常冉, 靖华芳, 高轶, 张思雨, 王越, 吴娟()   

  1. 中国康复研究中心北京博爱医院泌尿康复科,北京市 100068
  • 收稿日期:2024-09-23 修回日期:2025-01-10 出版日期:2025-02-25 发布日期:2025-02-25
  • 通讯作者: 吴娟,E-mail: juanwu7070@126.com
  • 作者简介:常冉(1997-),女,汉族,北京市人,硕士,医师,主要研究方向:泌尿康复与神经泌尿。
  • 基金资助:
    中国康复研究中心重点课题(2021zx-12)

Predictive value of bladder deformation index for upper urinary tract damage in neurogenic bladder patients

CHANG Ran, JING Huafang, GAO Yi, ZHANG Siyu, WANG Yue, WU Juan()   

  1. Department of Urological Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2024-09-23 Revised:2025-01-10 Published:2025-02-25 Online:2025-02-25
  • Contact: WU Juan, E-mail: juanwu7070@126.com
  • Supported by:
    China Rehabilitation Research Center Project (Key)(2021zx-12)

摘要:

目的 评估膀胱变形指数(BDI)在判断神经源性膀胱(NB)患者上尿路损伤方面的预测价值。

方法 回顾性分析2015年1月至2018年12月北京博爱医院收治的87例NB患者,根据是否存在肾积水分为上尿路损伤组和上尿路正常组。收集患者人口统计学、生化参数和影像尿动力学(VUDS)数据,计算BDI。比较两组一般特征和VUDS参数,对有统计学意义的数据采用受试者工作特征(ROC)曲线进行评价。

结果 87例患者中,上尿路损伤组54例,上尿路正常组33例。两组病程、肌酐水平和BDI有显著性差异(P < 0.05),ROC曲线下面积分别为0.686、0.836和0.928。

结论 NB患者病程、肌酐水平和BDI与上尿路损伤有关,BDI的敏感性和特异性最高,可能对定量膀胱造影和诊断上尿路损伤有一定意义,有待进一步研究。

关键词: 神经源性膀胱, 下尿路功能障碍, 上尿路, 膀胱变形指数

Abstract:

Objective To assess the predictive value of the bladder deformation index (BDI) in determining upper urinary tract (UUT) damage among patients with neurogenic bladder (NB).

Methods Clinical data of 132 NB patients admitted to Beijing Bo'ai Hospital from January, 2015 to December, 2018 were retrospectively analyzed. Patients were divided into UUT damage group and normal UUT group according to the presence or absence of hydronephrosis. The demographics, biochemical parameters and video-urodynamics (VUDS) findings were collected, and BDI was calculated. Receiver operating characteristic (ROC) curves were utilized to evaluate the predictive capability.

Results There were 54 patients in UUT damage group and 33 in normal UUT group. The course of disease, creatinine level and BDI were siginificantly different between two groups (P < 0.05), while the area under the curve were 0.686, 0.836 and 0.928, respectively.

Conclusion Course of disease, creatinine level and BDI are associated with UUT damage in NB patients, and BDI demonstrates the highest sensitivity and specificity, which may play a role in diagnosis of UUT damage.

Key words: neurogenic bladder, lower urinary tract dysfunction, upper urinary tract, bladder deformation index

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