重视中西医结合脑-肢体协同的时空效应及其机制研究

doi:10.3969/j.issn.1006-9771.2025.10.001

《中国康复理论与实践》 ›› 2025, Vol. 31 ›› Issue (10): 1117-1120.doi: 10.3969/j.issn.1006-9771.2025.10.001

• 专题　脑-肢体协同的功能性近红外光谱研究 • 上一篇下一篇

重视中西医结合脑-肢体协同的时空效应及其机制研究

燕铁斌¹^,²(), 许琦³^,⁴

1.中山大学孙逸仙纪念医院康复医学科，广东广州市 510120
2.广东省康复与养老工程技术研究中心，广东广州市 510120
3.厦门市第五医院，福建厦门市 361101
4.厦门医学院临床医学院，福建厦门市 361023

收稿日期:2025-07-24 修回日期:2025-09-10 出版日期:2025-10-25 发布日期:2025-11-10
通讯作者: 燕铁斌，E-mail： dr.yan@126.com
作者简介:燕铁斌(1956-)，男，汉族，江苏南京市人，博士，教授、主任医师，博士研究生导师，主要研究方向：神经康复、骨科康复、运动损伤康复、老年病康复。
基金资助:
1.福建省科技计划项目(2022Y01020084);2.国家自然科学基金项目(81772447)

Spatiotemporal effect and mechanism of the integrated traditional Chinese and Western medicine brain-limb coordinated rehabilitation

YAN Tiebin¹^,²(), XU Qi³^,⁴

1. Department of Rehabilitation Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510120, China
2. Guangdong Provincial Engineering Research Center for Rehabilitation and Elderly Care, Guangzhou, Guangdong 510120, China
3. The Fifth Hospital of Xiamen, Xiamen, Fujian 361101, China
4. Department of Clinical Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China

Received:2025-07-24 Revised:2025-09-10 Published:2025-10-25 Online:2025-11-10
Contact: YAN Tiebin, E-mail: dr.yan@126.com
Supported by:
Fujian Science and Technology Planning(2022Y01020084);National Natural Science Foundation of China(81772447)

摘要/Abstract

摘要：

中西医结合脑-肢体协同康复技术的理论框架涵盖4类空间组合(脑区西医/中医+上肢/下肢中医/西医)和3种时序(先脑/先肢/同步)构成的12种干预模式，表现出显著的条件依赖性(如病种、疗程、基线状态)和人群异质性。经颅直流电刺激联合肢体康复在某些情况下可产生协同增效，但也可能出现有限增益或拮抗效应。目前特别缺乏系统比较先脑/先肢/同步不同时序效果的临床研究。功能性近红外光谱已被较成熟地应用于揭示脑-肢体协同康复技术的脑功能调控机制。

关键词: 脑-肢体协同调控技术, 中西医结合, 经颅直流电刺激, 时空组合效应

Abstract:

The theoretical framework of the integrated traditional Chinese medicine (TCM) and Western medicine brain-limb coordinated rehabilitation encompasses twelve intervention models, formed by combining four spatial combinations (brain-area Western medicine/TCM + upper/lower limb intervention of TCM/Western medicine) and three temporal sequences (brain-first, limb-first and simultaneous), exhibiting significant condition dependence (e.g., types of disease, treatment course, baseline status) and population heterogeneity. Transcranial direct current stimulation combined with limb rehabilitation can produce synergistic effects in some cases, but may also result in limited benefits or antagonistic effects. Currently, there is a particular lack of clinical studies that systematically compare the effects of different temporal sequences (brain-first, limb-first, simultaneous). Functional near-infrared spectroscopy has been relatively maturely applied to reveal the brain function regulation mechanisms underlying brain-limb coordinated rehabilitation.

Key words: brain-limb coordinated rehabilitation, integrated traditional Chinese medicine and Western medicine, transcranial direct current stimulation, spatiotemporal combinatorial effects

中图分类号:

R493

燕铁斌, 许琦. 重视中西医结合脑-肢体协同的时空效应及其机制研究[J]. 《中国康复理论与实践》, 2025, 31(10): 1117-1120.

YAN Tiebin, XU Qi. Spatiotemporal effect and mechanism of the integrated traditional Chinese and Western medicine brain-limb coordinated rehabilitation[J]. Chinese Journal of Rehabilitation Theory and Practice, 2025, 31(10): 1117-1120.

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重视中西医结合脑-肢体协同的时空效应及其机制研究

Spatiotemporal effect and mechanism of the integrated traditional Chinese and Western medicine brain-limb coordinated rehabilitation

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