《中国康复理论与实践》

《中国康复理论与实践》 ›› 2025, Vol. 31 ›› Issue (12): 1398-1413.doi: 10.3969/j.issn.1006-9771.2025.12.004

• 专题　运动干预在康复中的应用 • 上一篇    下一篇

运动干预对唐氏综合征儿童青少年多维健康结局影响的Meta分析

刘东斐, 颜会义, 杨帆(), 张帅   

  1. 云南师范大学体育学院，云南昆明市 650500
  • 收稿日期:2025-09-01 修回日期:2025-10-17 出版日期:2025-12-25 发布日期:2025-12-29
  • 通讯作者: 杨帆 E-mail:610204995@qq.com
  • 作者简介:刘东斐(1998-)，男，汉族，山西长治市人，博士研究生，主要研究方向：运动行为与健康促进。
  • 基金资助:
    新疆生产建设兵团社科基金项目(23YB13)

Effect of exercise interventions on multidimensional health outcomes in children and adolescents with Down syndrome: a meta-analysis

LIU Dongfei, YAN Huiyi, YANG Fan(), ZHANG Shuai   

  1. College of Physical Education, Yunnan Normal University, Kunming, Yunnan 650500, China
  • Received:2025-09-01 Revised:2025-10-17 Published:2025-12-25 Online:2025-12-29
  • Contact: YANG Fan E-mail:610204995@qq.com
  • Supported by:
    Project of Xinjiang Production and Construction Corps Social Science Fund(23YB13)

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摘要：

目的 系统评价运动干预对唐氏综合征儿童青少年多维度健康指标的影响。
方法 检索中国知网、万方数据库、维普、中国生物医学文献数据库、Web of Science、PubMed、Cochrane Library、Embase等数据库关于运动干预对唐氏综合征儿童青少年健康效果的文献，检索时限从建库至2025年8月10日，依据PICOS原则进行文献筛选，运用Cochrane偏倚风险评估工具进行文献质量评价，采用Stata 18.0和RevMan 5.4进行统计分析与发表偏倚检验。
结果 共纳入30篇文献，涉及32项研究，1 057例受试者。Meta分析结果显示，与对照组相比，运动干预可以改善唐氏综合征儿童青少年的身体成分、平衡功能、粗大运动技能和下肢肌肉力量(P < 0.05)。亚组分析提示，12~24周、每周1~2次、每次≤ 30 min的抗阻训练方案在改善体质量指数方面效果更佳；24~36周、每周3~4次、每次30~60 min的有氧运动方案在降低体脂率方面效果更佳；≤ 12周、每周3~4次、每次30~60 min的有氧运动方案在提升静态平衡功能方面效果更佳，而每次≤ 30 min的有氧运动方案在提升动态平衡和功能平衡方面效果最佳；≤ 12周、每周3~4次、每次> 60 min的有氧运动方案在促进粗大运动功能发展方面效果更佳；≤ 12周、每周3~4次、每次≤ 30 min的振动训练方案在增强膝关节屈伸肌群力量方面效果更佳。
结论 运动干预可安全有效地改善唐氏综合征儿童青少年身体成分、平衡功能、粗大运动技能和下肢肌肉力量。针对不同健康结局，存在效果更优的特定运动类型和剂量参数。

关键词: 儿童, 青少年, 唐氏综合征, 运动, 健康结局, Meta分析

Abstract:

Objective To systematically evaluate the effect of exercise interventions on multidimensional health indicators in children and adolescents with Down syndrome (DS).
Methods Literatures about exercise interventions on multidimensional health outcomes in children and adolescents with DS were searched in CNKI, Wanfang data, VIP, China Biology Medicine disc, Web of Science, PubMed, Cochrane Library, Embase and other databases from establishment to August 10, 2025, according to PICOS. The Cochrane Risk of Bias Assessment Tool was used to evaluate the quality of the literatures, and Stata 18.0 and RevMan 5.4 were used for statistical analysis and publication bias test.
Results A total of 32 studies with 1 057 subjects from 30 publications were included. Meta-analysis showed that exercise intervention significantly improved body composition, balance function, gross motor skills and lower limb muscle strength in children and adolescents with DS compared to the control group (P < 0.05). Subgroup analyses suggested that the resistance training program of 12 to 24 weeks, one to two times per week, ≤ 30 minutes in a single session was more effective on body mass index; the aerobic exercise program of 24 to 36 weeks, three to four times per week, 30 to 60 minutes in a single session was more effective on body fat percentage; the aerobic exercise program of ≤ 12 weeks, three to four times per week, 30 to 60 minutes in a single session was more effective on static balance function, while the aerobic exercise program with a single session of ≤ 30 minutes was the most effective on dynamic and functional balance; the aerobic exercise program with ≤ 12 weeks, three to four times per week, and a single session of more than 60 minutes was more effective on the development of gross motor function; and the vibration training program with ≤ 12 weeks, three to four times per week, and a single session of ≤ 30 minutes was more effective on the strength of knee flexor and extensor muscle groups.
Conclusion Exercise interventions can safely and effectively improve body composition, balance function, gross motor skills and lower extremity muscle strength in children and adolescents with DS. There are specific exercise types and dosage parameters that are more effective on different health outcomes.

Key words: children, adolescents, Down syndrome, exercise, health outcome, meta-analysis

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