《中国康复理论与实践》

《中国康复理论与实践》 ›› 1999, Vol. 5 ›› Issue (03): 106-109.

• 论著 • 上一篇    下一篇

体内可分解性高分子材料的研究:聚DL乳酸膜In Vitro降解特征

张颖; 朴东旭; 毛立江   

  1. 中国康复研究中心医用高分子研究室
  • 收稿日期:1998-12-07 出版日期:1999-09-25 发布日期:1999-09-25

Studies on biodegradable polymers in vitro degradation of poly(DL lactide)films

Zhang Ying,Piao Dongxu,Mao Lijiang   

  1. Chinese Journal of Rehabilitation Theory & Practice.-1999,5(3):106～109
  • Received:1998-12-07 Published:1999-09-25 Online:1999-09-25

PDF (PC)

被引次数

12

摘要： 本文主要讨论PDLLA膜in vitro 降解的一些特征，用分子量、分散指数和失重率等表示降解的规律和趋势，并对其降解机理进行初步讨论，认为PDLLA in vitro 降解是一个简单的酯键水解，水解反应是由末端羧基引起的自发催化反应。

关键词: PDLLA膜, 降解, 聚交酯, 乳酸, 分子量, 分散指数, 失重率

Abstract: In the paper,in vitro degradation of DL polylactic acid (PDLLA) film was studied.Regulation and tendency of degradation were showed by molecular weight regulator and monomer ration mass lossing.Degradation mechanism was discussed in light.It was thought that degradation of PDLLA in vitro was a simple hydrolysis reaction.The hydrolysis reaction was self catalytic reaction caused by terminal carboxyl group.

Key words: PDLLA film, degradation, polylactic acid, lactic acid, molecular weight, regulator and monomer ration, mass lossing.