《中国康复理论与实践》

《中国康复理论与实践》 ›› 1999, Vol. 5 ›› Issue (04): 145-149.

• 论著 •    下一篇

表面润滑型聚乙烯醇水凝胶医用导管的力学性能研究

毛立江; 胡元洁; 朴东旭; 孙瑞焕; 陈晓东; 张颖   

  1. 中国康复研究中心 医用高分子研究室
  • 收稿日期:1999-08-25 出版日期:1999-12-25 发布日期:1999-12-25

Study on the mechanical properties of surface-lubricated catheter made of PVA hydrogel

Mao Lijiang,Hu Yuanjie,Piao Dongxu,et al   

  1. Chinese Journal of Rehabilitation Theory & Practice.-1999,5(4):145～149
  • Received:1999-08-25 Published:1999-12-25 Online:1999-12-25

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摘要： 制备了两种高分子水凝胶弹性体构成的医用导管，考察了其力学性能。将30％Wt聚乙烯醇水溶液注模后，反复冻结、缓慢解冻，得到一种水凝胶管（A）。将聚乙烯醇（30％Wt）、二甲基亚砜（10％Wt）和水（60％Wt）加热、溶解、注模、冷却，得到另一种水凝胶管（B）。这两种水凝胶管的强度（30～40MPa）和伸度（350％～400％）均与市售的硅橡胶管和聚氯乙烯导管相仿；但是就弹性模量而言，（B）管为10MPa，与硅橡胶管相近，（A）管只有4MPa。γ-射线灭菌使这两种高分子水凝胶管的强度损失达40％～50％；而洗必太水溶液灭菌对它们的力学性能没有影响。两种水凝胶管的力学性能上的显著差异归因于PVA大分子的取向及结晶结构不同所致。

关键词: 聚乙烯醇水凝胶弹性体, 医用导管, 弹性模量, 应力应变

Abstract: Two types of catheter made of polymeric hydrogel were prepared and their mechanical properties were studied. The results showed PVA hydrogel catheter was prepared by repeated freezing-thawing cycles of PVA solution in mould. Another type of catheter (PVA-DMSO - hydrogel ) was prepared by cooling the PVA solution containing 10%wt DMSO in mould. The tensile strength (30～40MPa)and elongation(380 %～400%) of these two types of catheter were comparable with those of commercial PVC catheter and silicone rubber catheter. But the elastic modulus of PVA-DMSO hydrogel catheter was 10MPa,near to silicone rubber catheter and that of PVA hydrogel catheter was only 4MPa. γ-ray irradiation for sterile made 40%～50% loss of tensile strength for both catheter. Dipping in hibitane aqueous solution didn\'t affect mechanical properties.The obvious difference in mechanical properties was due to the difference in the orientation of PVA molecule chain and crystalline structure.

Key words: PVA hydrogel elastomer, catheter, elastic modulus, stress-strain