《中国康复理论与实践》 ›› 2000, Vol. 6 ›› Issue (04): 153-155.

• 康复治疗 • 上一篇    下一篇

脑通在重型颅脑损伤患者认知障碍中的应用

张建宏1; 范建中1; 蒋彬2   

  1. 1.广州第一军医大学南方医院康复科 广州;2.广西桂林地区人民医院康复科 桂林 541001
  • 收稿日期:2000-07-31 出版日期:2000-12-25 发布日期:2000-12-25

The effect of nicergoline on cognitive dysfunction in the severe traumatic brain injury

ZHANG Jianhong,FAN Jianzhong,JIANG Bin   

  1. Chinese Journal of Rehabilitation Theory & Practice.-2000,6(4):153~155
  • Received:2000-07-31 Published:2000-12-25 Online:2000-12-25

摘要: 目的:探讨脑通对重型颅脑损伤恢复期患者认知障碍的治疗作用及其机理。方法:将52例重型颅脑损伤恢复期患者分为常规治疗组和脑通治疗组,治疗前后检测SPECT并评估认知功能,分析脑局部血流量及认知功能的变化。结果:脑通组与常规组治疗后SPECT检查显示病灶数均有明显减少,但两者比较无统计学差异。脑通组治疗后认知功能评分较常规组高,虽然总体评分无统计学差异,但脑通组定向力及记忆力改善优于常规组(P<0.05)。结论:脑通可改善重型颅脑损伤患者的认知功能。

关键词: 脑通, 颅脑损伤, 认知, SPECT

Abstract: Objective:To explore the therapeutic effect and mechanism of nicergoline on the severe traumatic brain injury. Methods:52 TBI patients were divided into the routine treatment group and nicergoline treatment group. Before and after rehabilitation treatment the SPECT and cognitive function were assessed. Results:The lesions were both decreased in nicergoline group and routine group in SPECT scanning, but there was no difference in statistics. The value of cognitive function of the nicergoline treatment group, especially function-oriented and memory, was higher than that of the routine treatment group(P<0.05).Conclusions:The nicergoline can improve cognitive function of the severe traumatic brain injury.

Key words: nicergoline, traumatic brain injury, cognitive function, radionuclide imaging, tomography, emission computed, single phot