《中国康复理论与实践》 ›› 2001, Vol. 7 ›› Issue (01): 19-20.

• 专题研究 • 上一篇    下一篇

急性脑梗死事件相关电位与认知障碍

战翠英1; 张桂芳1; 石秉霞2   

  1. 1.青岛大学医学院 山东青岛市 266003;2.青岛大学医学院脑血管病研究所 山东青岛市 266003
  • 收稿日期:2000-12-20 出版日期:2001-03-25 发布日期:2001-03-25

Study on the correlation between the cognitive disorder and P300 in patients with acute brain infarction

ZHAN Cui-ying,ZHANG Gui-fang,SHI Bing-xia   

  1. Medical College of Qingdao University,Qingdao 266003
  • Received:2000-12-20 Published:2001-03-25 Online:2001-03-25

摘要: 目的分析脑梗死患者的事件相关电位与认知障碍的关系。方法应用简易精神状态检查量表(MMSE)和相关事件电位(ERP)的检测,分析脑梗死患者的认知功能变化。结果脑梗死组 (32例)与对照组(32例)之间P300潜伏期(P300PL)的比较有非常显著性差异(P<0.01)。从波形看,脑梗死组波幅较低,P300波变异大,波形不规则。两组MMSE评分亦有非常显著性差异(P<0.01)。脑梗死组P300潜伏期与MMSE评分呈负相关(r=-0.28,P<0.01)。结论P300潜伏期可客观地反映急性期脑梗死患者的认知功能障碍。

关键词: P300, 认知障碍, 急性脑梗死

Abstract: Objective To study the cognitive disorder in acute brain infarction. MethodCognition was meaured by P300 Peak Latency and The MMSE Scale for 32 patients with acute brain infarction. Results There are significant difference in P300 Peak Latency and The MMSE Scale scores between the patients and controls. ConclusionP300 Peak Latency could indicate the cognitive disorder in patients with acute brain infarction.

Key words: P300, cognitive disorder, acute brain infarction