《中国康复理论与实践》 ›› 2001, Vol. 7 ›› Issue (03): 122-123.

• 论著 • 上一篇    下一篇

合成型眼内黏弹剂的制备

孙瑞焕; 咸文淑; 朴东旭; 陈晓东   

  1. 中国康复医学研究所高分子材料研究室 北京市 100077
  • 收稿日期:2001-03-06 出版日期:2001-09-25 发布日期:2001-09-25

Preparation of artificial viscoelastic agent

SUN Rui-huan,XIAN Wen-shu,PIAO Dong-xu,et al   

  1. Biomedical Polymer Laboratory,China Research Institute of Rehabilitation Medicine, Beijing 100077, China
  • Received:2001-03-06 Published:2001-09-25 Online:2001-09-25

摘要: 目的制备可替代Healon的合成型眼内黏弹剂。方法采用自由基聚合法得到聚丙烯酰胺水溶液,以透析法将其进行精制,可有效地分离单体。结果与结论采用透析法制备合成型眼内黏弹剂在制造成本、重复性和储存稳定性上优于Healon.

关键词: 聚丙烯酰胺水溶液, 眼内黏弹剂, 实验

Abstract: ObjectiveTo prepare artificial viscoelastic agent used in ophthalmic operation as a substitute of Healon. MethodsPolyacrylamide was synthesized in aqueous solution of acrylamide. Residual monomer(Am) was separated from polymer by a novel method, extraction by semi permeable film. Results and ConclusionsArtificial viscoelastic agent prepared has advantages on cost of manufacture, processing repeatability and stability of storage comparing to Healon.

Key words: polyacrylamide solution, ophthalmic viscoelastic agent, experiment