《中国康复理论与实践》

《中国康复理论与实践》 ›› 2003, Vol. 9 ›› Issue (06): 328-329.

• 神经康复 • 上一篇    下一篇

肉毒毒素A治疗痉挛型脑瘫探讨

杜凤珍; 路生禄; 王惠英; 席彩萍; 丁吉芳; 姜艳; 安超文; 魏玉香   

  1. 甘肃省康复中心脑瘫康复研究所 甘肃兰州市 730000
  • 收稿日期:2003-03-18 出版日期:2003-06-25 发布日期:2003-06-25

Observation of botulinum toxin A applying in treatment of spastic cerebral palsy

DU Feng-zhen,LU Sheng-lu,WANG Hui-ying,et al   

  1. Institute of Cerebral Palsy Rehabilitation of Gansu Rehabilitation Center,Lanzhou 730000,Gansu,China
  • Received:2003-03-18 Published:2003-06-25 Online:2003-06-25

PDF (PC)

被引次数

6

摘要： 目的探讨肉毒毒素 A(botulinum toxin A,BTX-A)在脑瘫康复治疗中的应用价值。方法将47例痉挛型脑瘫儿童随机分为治疗组(32例)和对照组(15例),两组均接受正规康复训练,治疗组辅以痉挛肌注射BTX-A,观察两组患儿的内收肌角与日常生活活动能力(activities of daily living,ADL)变化。结果治疗3个月和6个月后,治疗组患儿的内收肌角、ADL 改善情况明显优于对照组(P<0.01)。结论康复训练仍是有效的脑瘫治疗手段,BTX-A局部注射作为一种重要的辅助方法,可为康复训练提供良好时机,两者结合可明显缩短疗程、提高疗效,在脑瘫康复治疗中具有应用价值。

关键词: 脑性瘫痪, 肉毒毒素A, 痉挛, 日常生活活动能力

Abstract: ObjectiveTo observe the effect of botulinum toxin A (BTX-A) in rehabilitation training on cerebral palsy (CP).Methods47 CP children were randomly divided into the treatment group (32 cases) and control group (15 cases). Both groups were received rehabilitation training. But cases of the treatment group were injected with BTX-A in part of spastic muscles. Angles of inner contraction muscle (AICM) and activities of daily living (ADL) of two groups were observed for 6 months.ResultsImprovements of AICM and ADL in the treatment group were significantly better than that in the control group (P<0.01).Conclusions The rehabilitation training still is a kind of efficient treatment method. BTX-A injecting in part of spastic muscles is a kind of efficient assistant method and furnishes a better chance for rehabilitation training. Rehabilitation training combining with BTX-A injection can clearly curtail period of treatment, raise curative effect. BTX-A injection has significant applicable value in treatment on cerebral palsy.

Key words: cerebral palsy, botulinum toxin A(BTX-A), spasm, activities of daily living (ADL)