《中国康复理论与实践》

《中国康复理论与实践》 ›› 2003, Vol. 9 ›› Issue (10): 623-625.

• 脑卒中康复 • 上一篇    下一篇

脑出血性梗死及其相关因素分析

张晓燕; 苏闻; 盛爱珍; 陈海波   

  1. 北京医院脑系科 北京市 100730
  • 收稿日期:2003-08-11 出版日期:2003-10-25 发布日期:2003-10-25

Analysis of cerebral hemorrhagic infarction and relative factors in acute ischemic stroke

ZHANG Xiao-yan, SU Wen, SHENG Ai-zhen, et al   

  1. Department of Neurology, Beijing Hospital, Beijing 100730, China
  • Received:2003-08-11 Published:2003-10-25 Online:2003-10-25

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摘要： 目的应用“脑卒中急性期患者数据库”分析脑出血性梗死(HI)及相关因素。方法从数据库中选取发病3天以内的缺血性脑血管病患者1487例,分析HI的发生频率和程度。结果发生HI的患者占11%,其中51%为心源性脑血管栓塞患者;心源性脑血管栓塞患者中HI的发生率为28%,其中轻度67%、中度23%、形成血肿10%;高龄、人工瓣膜、入院时病情程度评分是HI的独立相关因素。HI越重,康复效果越差;使用血栓溶解药物的患者虽有HI增多倾向,但多数患者出院时功能障碍较轻。结论“脑卒中急性期患者数据库”的建立有助于对脑卒中的诊断、分析和管理,对临床治疗有指导意义。

关键词: 出血性梗死, 急性脑卒中, 心源性脑栓塞, 溶栓治疗, 危险因素

Abstract: ObjectiveTo analyze cerebral hemorrhagic infarction (HI) and relative factors with the database of Standard Stroke Registry (SSR).Methods1 487 consecutive patients with acute ischemic stroke admitted within 3 days after onset were analyzed with SSR.ResultsHI was observed in 11% of patients, of whom 51% were diagnosed as having cardiogenic embolism. In patients with supratentorial infarction of cardiac origin, 28% had HI (mild 67%, moderate 23, hematoma 10%). On multiple logistic regression analysis, independent factors related with HI were found to be age, prosthetic cardiac valve and NIHSS scores at admission. Patients with more severe HI were associated with a poorer outcome at discharge. Clinical outcome tended to be better in patients receiving thrombolytic agents than in those without receiving agents, while the incidence of HI was slightly more frequent in the former.Conclusion It is confirmed that the SSR database is useful for understanding and analyzing the status of stroke diagnosis and management throughout the nation, and revisions are needed in some formats.

Key words: hemorrhagic infarction, acute stroke, cardiogenic brain embolism, thrombolytic therapy, risk factor