《中国康复理论与实践》

《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (01): 59-60.

• 临床康复 • 上一篇    下一篇

PET和EEG在顽固性癫痫诊断中的价值

初君盛; 张斌; 白勤; 崔瑞雪; 王忠诚   

  1. 首都医科大学附属北京天坛医院、北京市神经外科研究所 北京市 100050
  • 收稿日期:2003-12-12 出版日期:2004-01-25 发布日期:2004-01-25

FDG-positron emission tomography and EEG:The comparison in localizing in refractory epilepsy

CHU Jun-sheng, ZHANG Bin, BAI Qin,et al   

  1. Beijing Neurosurgical Institution,Beijing 100050,China
  • Received:2003-12-12 Published:2004-01-25 Online:2004-01-25

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摘要： 目的探讨电视录像-动态脑电图监测(VEEG)和正电子发射断层扫描(PET)在癫痫灶定位诊断中的价值及两者之间的联系。方法44例顽固性癫痫患者,经VEEG及PET检查定位,对两者的一致性进行了比较。在其中38例进行了癫痫外科手术治疗的患者中进一步记录了术中ECoG和术后病理,与上述两者进行比较。结果PET阳性率为98% ,EEG为95%;两者完全一致和部分一致率分别为50%和23%。在PET和EEG定位完全不一致的12例手术患者中,8例术中ECoG与PET相符,2例与EEG相符。结论PET是诊断癫痫病灶灵敏有效的一种无创性检查,在EEG不能定位的患者中,能够提供有价值的补充信息。

关键词: 正电子发射断层扫描(PET), 视频脑电图, 癫痫, 脑外科

Abstract: ObjectiveTo study the values of EEG and [18F]2-deoxyglucose(FDG) positron emission tomography in localizing the epiletogenic cortex,and evaluate their relation.MethodsVideo-EEG(VEEG) and FDG-PET scans were performed in 44 patients with refractory epilepsy.Electrocorticography(ECoG) in surgery and patholopy were performed in 38 patients who had undergone neurosurgical therapy.Congruence among them were studied.Results43 patients(98%) had FDG-PET hypometabolism.42 patients(95%) had epileptiform wave.There were 22 patients(50%) whose PET and EEG were in complete congruence,whereas 10 patients(23%) in part congruence.12 patients who had undergone operation had controversial results in PET and EEG,8 cases had agreement between ECoG and PET,and 2 cases had agreement between ECoG and VEEG. ConclusionFDG-PET is a effective,sensitive and non-invasive investigation.It can provide valuable supplemental data in patients with unlocalized surface EEG.

Key words: positron emission tomography(PET), Video-EEG, epilepsy, neurosurgery