《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (03): 136-138.

• 专题 • 上一篇    下一篇

轻度认知功能障碍和轻度阿尔茨海默病患者的持续注意功能

周爱红; 王荫华   

  1. 北京大学第一医院神经内科 北京市 100034
  • 收稿日期:2003-11-06 出版日期:2004-03-25 发布日期:2004-03-25

Sustained attention for the patients with mild cognitive impairment and mild Alzheimer's disease

ZHOU Ai-hong, WANG Yin-hua   

  1. Department of Neurology, First Hospital,Peking University, Beijing 100034,China
  • Received:2003-11-06 Published:2004-03-25 Online:2004-03-25

摘要: 目的了解轻度认知功能障碍(MCI)和轻度阿尔茨海默病(AD)患者的持续注意功能。方法采用持续作业任务(CPT),对10例轻度AD患者、10例MCI患者和10例正常老年人进行对照研究。结果轻度AD患者的反应时显著长于对照组(P<0.001),漏报率高于对照组(P<0.05),虚报率与对照组无显著性差异(P=0.064),漏报率随时间延长增高。MCI组各指标与对照组无显著性差异。结论轻度AD患者存在持续注意功能障碍,MCI患者持续注意功能正常。

关键词: 阿尔茨海默病, 轻度认知功能障碍, 持续注意功能

Abstract: ObjectiveTo deter mine the sustained attention function of the patients with mild Alzheimer's disease(AD) and mild cognitive impairment(MCI).Methods10 patients with MCI, 10 with mild AD and other 10 healthy elderly controls were tested with Continuous Performance Task(CPT) aimed to assess sustained attention. ResultsCompared with the normal controls, the mild AD patients reacted very more slowly(P<0.001), missed more targets(P<0.05), while that the MCI patients did was as well as the control group. ConclusionThe mild AD patients shows impairment in sustained attention function, but the MCI patients shows a preserved ability of sustained attention function.

Key words: Alzheimer's disease(AD), mild cognitive impairment(MCI), sustained attention function