《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (05): 302-303.

• 临床研究 • 上一篇    下一篇

特发性肌肉颤搐的诊断与治疗

郭军红; 蒲传强; 贾渭泉; 吴卫平; 郎森阳; 于生元   

  1. 中国人民解放军总医院神经内科 北京市 100853
  • 收稿日期:2004-03-19 出版日期:2004-05-25 发布日期:2004-05-25

Idiopathic generalized myokymia:Diagnosis and treatment

GUO Jun-hong, PU Chuan-qiang, JIA Wei-quan, et al   

  1. Department of Neurology, General Hospital of PLA, Beijing 100853, China
  • Received:2004-03-19 Published:2004-05-25 Online:2004-05-25

摘要: 目的探讨特发性肌肉颤搐的临床特征、诊断与治疗。方法对7例特发性肌肉颤搐诊疗过程进行回顾性分析。结果7例均有典型的波动性和虫蠕状肌肉颤搐。全部病例的肌肉颤搐均出现在双侧腓肠肌,5例出现在双上肢,2例在面部、腰背部及腹部。肌肉颤搐在活动后可加重,在睡眠时仍持续存在。虫蠕状波动在肌肉松弛状态时更易观察。5例肌电图提示有肌肉颤搐放电,但2例肌电图表现正常。卡马西平或苯妥英钠治疗有明显效果。结论特发性肌肉颤搐具有特殊的临床表现,且有较好的治疗效果。

关键词: 特发性肌肉颤搐, 临床表现, 诊断, 治疗

Abstract: ObjectiveTo probe the clinical features,diagnosis and treatment of idiopathic generalized myokymia.MethodsSeven patients with idiopathic generalized myokymia were analysed retrospectively.ResultsAll 7 patients showed prominent myokymia characterized by undulating and vermicular movements spreading across the muscle surface. The myokymia in gastrocnemius muscles in all cases. The myokymia also appeared in both upper extremities in 5 patients,and in faces,waist,back,abdomen and all extremities in 2 patients. Muscle rippling movement was induced and increased by exercise,and persistent during sleep. The vermicular myokymia could be observed easily in the relaxation of the muscles. Electromyography tests showed myokymic discharges in 5 patients,but normal in 2 patients. 5 patients of them were cured with carbamazepine and phenytoin sodium.ConclusionThere are typical clinical features and effective treatment in the patients with idiopathic generalized myokymia.

Key words: idiopathic generalized myokymia, clinical features, diagnosis, treatment