《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (02): 141-142.

• 临床研究 • 上一篇    下一篇

糖皮质激素吸入疗法对小儿骨代谢和肾上腺功能的影响

陈焕芝; 冯益真; 王峻; 武际英   

  1. 山东大学济南市中心医院儿科 山东济南市 250013
  • 收稿日期:2004-10-25 出版日期:2005-02-25 发布日期:2005-02-25

Effect of glucocorticoid inhaled on bone metabolism, bone density and adrenal function in children with asthma

CHEN Huan-zhi,FENG Yi-zhen, WANG Jun, et al   

  1. Department of Pediatrics, Jinan Central Hospital, Shandong University, Jinan 250013,Shandong, China
  • Received:2004-10-25 Published:2005-02-25 Online:2005-02-25

PDF (PC)

被引次数

7

摘要： 目的 探讨糖皮质激素吸入疗法对哮喘患儿骨代谢、骨密度和肾上腺功能的影响。方法 60例哮喘患儿随机分为治疗组和对照组各30例,另设普通肺炎对照组30例。治疗组给予普米克气雾剂吸入治疗(200～600μg/d),必要时高压雾化吸入β2激动剂或吸入β2激动剂气雾剂,口服西替利嗪;对照组不吸入普米克,其他处理同治疗组。比较 3组患儿的骨代谢、骨密度和肾上腺功能。结果 治疗18个月后,3组患儿的骨代谢、骨密度和肾上腺功检测指标无显著性差异(P>0.05)。结论 哮喘患儿接受糖皮质激素吸入治疗是安全的。

关键词: 哮喘, 小儿, 糖皮质激素

Abstract: ObjectiveTo explore the effect of glucocorticoid inhaled on bone metabolism, bone density and adrenal function in children with asthma.Methods60 children were randomly divided into the treatment group and control group with 30 cases in each group, and having 30 pneumonia children as another control. Children of the treatment group were treated with budesonide (200～600 μg/d) inhaled, asthma cases in the control group without budesonide inhaled. Bone metabolism, bone density and adrenal function of children in three groups were compared.ResultsAfter 18 months treatment, there were no significantly differences of bone metabolism, bone density and adrenal function among children of three groups (P>0.05).ConclusionThe treatment of glucocorticoid inhaled is safe to asthma children.

Key words: asthma, children, glucocorticoid