《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (05): 366-368.

• 临床研究 • 上一篇    下一篇

中国健康成人大脑中央前回质子磁共振波谱研究

王惠芳; 郎宁; 宋红松; 王力平; 刘小璇; 张俊; 康德; 李选; 樊东升   

  1. 1.北京大学第三医院神经科 北京市 100083;2.北京大学第三医院放射科 北京市 100083;3.北京大学首钢医院神经内科 北京市 100041
  • 收稿日期:2005-01-13 出版日期:2005-05-25 发布日期:2005-05-25

Characteristics of proton magnetic resonance spectroscopy on precentral gyrus in 92 healthy Chinese adults

WANG Hui-fang, LANG Ning, SONG Hong-song, et al   

  1. Neurological Department, Peking University third Hospital,100083 Beijing, China
  • Received:2005-01-13 Published:2005-05-25 Online:2005-05-25

PDF (PC)

被引次数

13

摘要： 目的运用质子磁共振波谱(1H-MRS)研究中国健康成人大脑中央前回脑组织代谢物的特点,为疾病研究提供正常参照。方法对92名健康成年志愿者进行双侧中央前回1H-MRS检测,对比分析其大脑中央前回脑组织的NAA/Cr、Cho/Cr和NAA/Cho值。结果不同侧别和不同性别之间的NAA/Cr、Cho/Cr和NAA/Cho值均无显著性差异;NAA/Cr与年龄低度负相关,Cho/Cr与年龄低度正相关,NAA/Cho与年龄呈中度负相关。结论建立了健康成人大脑中央前回脑组织代谢物的参照特点

关键词: 健康成人, 中国, 质子磁共振波谱, 中央前回

Abstract: ObjectiveTo explore the characteristics of the metabolite concentrations of the precentral gyrus in healthy Chinese adults using proton magnetic resonance spectroscopy (1H-MRS).Methods 1H-MRS was carried out in 92 healthy Chinese adult volunteers. The metabolite ratios of NAA/Cr, Cho/Cr and NAA/Cho were compared and analysed.ResultsNo significant changes of NAA/Cr, Cho/Cr and NAA/Cho ratios were observed between the left and right precentral gyrus, nor between the male and female. However, the precentral gyrus NAA/Cr and NAA/Cho ratios were decreased gradually with aging and Cho/Cr ratios were increased gradually with aging.ConclusionThe characteristics of the precentral gyrus metabolite concentrations in healthy Chinese adults have been obtained.

Key words: healthy adults, Chinese, precentral gyrus, proton magnetic resonance spectroscopy