《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (02): 101-102.

• 专题 • 上一篇    下一篇

康复治疗联合A型肉毒毒素局部注射治疗痉挛型脑性瘫痪的疗效

高宝勤1a; 赵性泉1b; 谢建雷1b; 邓欣1a; 李孚伟1b   

  1. 1.首都医科大学附属北京天坛医院 a.儿科;b.神经内科, 北京市 100050
  • 收稿日期:2005-12-14 出版日期:2006-02-25 发布日期:2006-02-25

Effect of Rehabilitation and Local Injection of Botulinum Aoxic A on Spastic Cerebral Palsy

GAO Bao-qin, ZHAO Xing-quan, XIE Jian-lei, et al   

  1. The Department of Pediatrics, Beijing Tiantan Hospital Affiliated to Capital University of Medicine Science,Beijing 100050, China
  • Received:2005-12-14 Published:2006-02-25 Online:2006-02-25

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摘要： 目的观察康复治疗联合A型肉毒毒素(BTX-A)局部注射治疗痉挛型脑性瘫痪的疗效。方法60例脑性瘫痪患儿随机分为治疗组和对照组各30例。治疗组采用康复治疗联合BTX-A局部注射;对照组采用单纯康复治疗。治疗12周后比较两组患儿的关节屈曲度、步态等临床指标。结果治疗组患儿各项临床评价指标的改善优于对照组(P<0.05)。结论康复治疗联合BTX-A局部注射可提高脑性瘫痪的疗效。

关键词: 脑性瘫痪, 痉挛, A型肉毒毒素, 康复治疗

Abstract: ObjectiveTo evaluate the efficacy of rehabilitation associated with local intramuscular injection of botulinum toxic A (BTX-A) on spastic cerebral palsy (CP).Methods60 children with spastic CP were divided into experimental group and control group with 30 cases in each group. Cases of experimental group were treated with rehabilitation associated with local intramuscular injection of BTX-A. Cases of control group were treated only with rehabilitation treatment. The therapeutic efficacies of two groups were evaluated with physician rating scale (PRS) and activities of daily living (ADL) evaluation systems.ResultsImprovement of clinical evaluations index-PRS and ADL in experimental group was much more significant than that of control group (P<0.05). ConclusionRehabilitation associated with local intramuscular injection of BTX-A can improve the efficacy of spastic CP.

Key words: cerebral palsy, spasm, botulinum toxic A (BTX-A), rehabilitation treatment