《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (04): 277-279.

• 专题 •    下一篇

失匹配正波——视觉失匹配电位研究

楚向丽1,2; 王荫华2; 王玉平2   

  1. 1.首都医科大学宣武医院神经内科 北京市 100053;2.北京大学第一医院神经内科 北京市 北京市 100034
  • 收稿日期:2006-02-21 出版日期:2006-04-25 发布日期:2006-04-25

Mismatch Positivity: Mismatch Component in Visual Modality

CHU Xiang-li, WANG Yin-hua, WANG Yu-ping   

  1. The Department of Neurology, Peking University First Hospital, Beijing 100034, China
  • Received:2006-02-21 Published:2006-04-25 Online:2006-04-25

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摘要： 目的探讨视觉模式中是否存在与听觉失匹配负波(MMN)类似的电位成分。方法采用多导脑电诱发电位工作站对15名健康成人进行事件相关电位研究。采用4种刺激对无差异(Nd)、轮廓差异(Cd)、形状差异(Sd)和双重差异(Dd),让受试者随机完成形状匹配作业和双重匹配作业。结果在P1-N1潜伏期内(100～140ms),有差异的3种状态(Cd、Sd和Dd)均诱发出一正波,即视觉失匹配正波(MMP),而Dd状态诱发的MMP波幅更大,是单特征差异(Cd、Sd)的MMP之和。结论视觉模式中,偏差刺激诱发的MMP可能是与听觉MMN类似的成分,反映了脑对视觉刺激变化的自动加工过程。

关键词: 事件相关电位, 视觉模式, 失匹配负波, 失匹配正波

Abstract: ObjectiveTo investigate if there were potential components similar to auditory mismatch negativity (MMN) in the visual modality.MethodsEvent-related potentials (ERP) of 15 healthy adults were tested. Subjects were demanded to complete shape-matching task and double-matching task under 4 kinds visual stimuli including no-difference (Nd), contour-difference (Cd), shape-difference (Sd) and double-difference (Dd).ResultsWithin P1-N1 latent period (100～140 ms), three kinds of deviant stimuli (Cd, Sd, Dd) elicited a positivity, mismatch positivity (MMP). MMP amplitude elicited by Dd was a sum elicited by Cd and Sd (single-difference).ConclusionIn the visual modality, MMP elicited by warp stimulus may be an element similar to auditory MMN and reflect auto-processing of brain to visual stimulus.

Key words: event-related potentials, visual modality, mismatch negativity, mismatch positivity