《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (06): 461-463.

• 专题 •    下一篇

踝臂指数对老年人冠状动脉狭窄程度的预测价值

杨士伟1; 胡大一1; 王显2; 张守彦3; 张健2; 郭实2   

  1. 1.北京大学人民医院心内科 北京市 100044;2.北京军区总医院心肺血管中心 北京市 100070;3.首都医科大学附属同仁医院心内科 北京市 100037
  • 收稿日期:2006-01-28 出版日期:2006-06-25 发布日期:2006-06-25

Usefulness of Ankle Brachial Index to Predict the Extent of Coronary Stenosis

YANG Shi-wei, HUDa-yi, WANG Xian, et al   

  1. The Department of Cardiology, People's Hospital of Peking University, Beijing 100044, China
  • Received:2006-01-28 Published:2006-06-25 Online:2006-06-25

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摘要： 目的观察老年患者踝臂指数(ABI)与冠状动脉狭窄程度的相关性,评价ABI对冠状动脉狭窄程度的预测价值。方法对118例连续入选冠状动脉造影患者进行ABI测量、病史采集及血液化验检查。结果ABI与Gensini评分呈显著负相关;冠状动脉三支或左主干病变患者ABI显著降低(P<0.001),而造影正常、单支病变或二支病变患者的ABI无显著性差异;评价ABI对三支或左主干病变预测价值的操作者工作特征曲线(ROC)下面积为0.75±0.045(95% CI=0.67～0.84,P<0.001);ABI≤0.9作为截断值预测三支或左主干病变具有相对高的特异度(89.1%)和敏感度(55.6%)。结论老年患者ABI与冠状动脉狭窄严重程度显著负相关,ABI≤0.90对预测冠状动脉三支和左主干病变具有较高的特异度和敏感度。

关键词: 踝臂指数, 冠状动脉造影, Gensini评分, 操作者工作特征曲线

Abstract: ObjectiveTo examine the relationship between ankle brachial index (ABI) and the extent of coronary stenosis and evaluate the usefulness of ABI to predict the extent of coronary stenosis in old patients.Methods118 patients with coronary angiography were examined by ABI and hemostatic factors evaluation in addition to history collection.ResultsABI was inversely and significantly associated with Gensini score. ABI reduced significantly (P<0.001) in the patients with 3-vessel or left main coronary artery disease (CAD). But there were no significant differences in ABI among the patients with no CAD, 1-vessel or 2-vessel CAD. The corresponding area under the ROC curve was 0.75±0.045, with 95% CI=0.67～0.84 (P<0.001) in ABI in 3-vessel or left main CAD. When ABI≤0.9, it had a relatively high specificity (89.1%) and sensitivity (55.6%) for predicting the presence of 3-vessel disease or left main CAD.ConclusionIn the old patients, ABI is inversely and significantly associated with the extent of coronary stenosis, and ABI≤0.9 has a relatively high specificity and sensitivity for predicting the presence of 3-vessel or left main CAD.

Key words: ankle-brachial index (ABI), coronary angiography, Gensini score, receiver-operating characteristic curves (ROC)