《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (06): 471-472.

• 专题 • 上一篇    下一篇

短潜时体感诱发电位评价冠心病患者中枢神经功能研究

田瑞振1; 郝媛媛2; 刘德山2   

  1. 1.河北省人民医院神经内二科 河北石家庄市 050051;2.山东大学齐鲁医院 山东济南市 250012
  • 收稿日期:2006-02-15 出版日期:2006-06-25 发布日期:2006-06-25

Short Latency Somatosensory Evoked Potentials in Evaluation of Central Nervous System Function of Patients with Coronary Cardiac Diease

TIAN Rui-zhen, HAO Yuan-yuan, LIU De-shan   

  1. People's Hospital of Hebei Province, Shijiazhuang 050051, Hebei,China
  • Received:2006-02-15 Published:2006-06-25 Online:2006-06-25

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被引次数

13

摘要： 目的应用短潜时体感诱发电位(SSEP)评价冠心病中枢神经功能的变化。方法刺激43例无明显中枢神经症状的冠心病患者(心绞痛18例、心肌梗死慢性期25例)以及14例正常对照的正中神经,同时记录皮质体感诱发电位和脊髓体感诱发电位,观察中枢神经功能的变化。结果心绞痛和心肌梗死患者的N13、N20、P25波潜伏期及中枢传导时间(CCT)均较对照组明显延长(P<0.05～0.001);心绞痛患者的N20、P25波潜伏期及CCT均较心肌梗死患者明显延长(P<0.01～0.001)。结论冠心病特别是心肌梗死患者,其脊髓到大脑皮质第一感觉区的中枢躯体感觉通路存在亚临床损害。

关键词: 缺血性心脏病, 短潜时体感诱发电位, 中枢传导时间, 中枢神经系统病变

Abstract: ObjectiveTo evaluate central nervous system function of patients with coronary cardiac diease by short latency somatosensory evoked potentials (SSEP).MethodsThe cerebral and spinal somatosensory evoked potentials were recorded by stimulating median nerve in 43 patients with coronary cardiac disease but without apparent nervous symptoms and 14 healthy control subjects.ResultsThe lactency periods and central conductive time of N13, N20 and P25 wave were significantly prolonged in patients with myocardial infarction (MI) or angina pectoris (AP) when compared with normal controls (P<0.05～0.001). The lactency periods and central conductive time of N20 and P25 wave recorded in MI patients were longer than those recorded in AP patients (P<0.01～0.001).ConclusionThe subclinical nervous damages in the central somatosensory pathway from spinal cord to cerebral cortex is present in patients with coronary cardiac disease especially myocardial infarction.

Key words: ischemic cardiac disease, short latency somatosensory evoked potentials, central conductive time, central nervous system disease