《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (06): 501-502.

• 临床研究 • 上一篇    下一篇

逍遥散联合百忧解治疗脑卒中后抑郁疗效观察

李瀛; 朱海勇; 高慧娟; 樊留博   

  1. 浙江省台州医院康复科 浙江临海市 317000
  • 收稿日期:2006-03-08 出版日期:2006-06-25 发布日期:2006-06-25

Effect of Xiaoyao Powder Combined with Prozac on Post-stroke Depression

LI Ying, ZHU Hai-yong, GAO Hui-juan, et al   

  1. The Department of Rehabilitation, Taizhou Hospital, Linhai 317000, Zhejiang, China
  • Received:2006-03-08 Published:2006-06-25 Online:2006-06-25

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摘要： 目的观察逍遥散联合百忧解辅以心理疗法治疗脑卒中后抑郁(PSD)及神经功能缺损的疗效。方法将85例PSD患者随机分为治疗组43例和对照组42例,在药物治疗基础上,对照组予百忧解配合心理治疗,治疗组在对照组的基础上加用逍遥散。治疗前后采用汉密尔顿抑郁量表(HAMD)、改良Barthel指数(MBI)、斯堪的纳维亚卒中量表(SSS)对患者进行评定,比较两组的疗效。结果治疗后,治疗组的有效率明显高于对照组(P<0.01),HAMD评分和SSS评分明显低于对照组(P<0.01),MBI评分明显高于对照组(P<0.01)。结论逍遥散联合百忧解并配以心理疗法治疗PSD不仅能明显改善患者的抑郁症状,而且能促进神经功能的恢复。

关键词: 脑卒中后抑郁, 逍遥散, 百忧解, 心理治疗

Abstract: ObjectiveTo observe the effect of Xiaoyao powder combined with prozac and psychological therapy on post-stroke depression (PSD).Methods85 PSD patients were randomly divided into the treatment group (n=43) and control group (n=42). All patients were treated with routine therapy, including prozac and psychological therapy. Patients in the treatment group were also given Xiaoyao powder. Scores of Hamilton Depression Scale (HAMD), modified Barthel index (MBI) and Scandinavian Stroke Scale (SSS) of all patients were evaluated before and after therapy.ResultsAfter treatment, the effective rate and MBI scores were significantly higher and scores of HAMD and SSS were significantly lower for patients of the treatment group compared with those of the control group (P<0.01).ConclusionXiaoyao powder combined with prozac and psychological therapy can improve depression and neural function of PSD patients significantly.

Key words: post-stroke depression, Xiaoyao powder, prozac, psychological therapy