《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (07): 608-609.

• 临床研究 • 上一篇    下一篇

静脉注射胺碘酮与心律平转复阵发心房颤动的疗效比较

李宗军; 王志   

  1. 北京博爱医院急诊科,北京市 100068
  • 收稿日期:2006-03-07 出版日期:2006-07-01 发布日期:2006-07-01

Comparison of the Effect of Amiodaron and Propafenone on Cardioversion of Paroxysmal Auricular Fibrillation

LI Zong-jun, WANG Zhi   

  1. Emergency Department of Beijing Charity Hospital, Beijing 100068, China
  • Received:2006-03-07 Published:2006-07-01 Online:2006-07-01

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摘要： 目的对比研究胺碘酮与心律平转复阵发心房颤动的疗效。方法阵发心房颤动(此次病程≤48h)患者58例随机分为两组胺碘酮组30例,给予胺碘酮负荷量150mg静注后,继以0.6～1.0mg/min维持点滴,依心室率情况调整胺碘酮剂量。心律平组28例,静脉给予心律平1.4～2.0mg/kg,5min内注射,继以0.28mg/min维持静点,无效者改用胺碘酮治疗。结果胺碘酮组转复成功率为86.7%(26/30),心律平组转复成功率57.1%(16/28),且心律平组转复心律失败的部分病例使用胺碘酮仍有效;胺碘酮组平均复律时间(101±95)min(6～508min),心律平组(172±148)min(11～608min)。结论胺碘酮在转复阵发心房颤动比心律平更加快速、安全、有效。

关键词: 心房纤维性颤动, 胺碘酮, 心律平, 复律

Abstract: ObjectiveTo compare the effect of amiodaron and propafenone on the cardioversion of paroxysmal auricular fibrillation (PAF). Methods58 PAF (≤48 h) cases were radomly divide into two groups: 30 cases who accepted amiodaron 150 mg intravenous injection, and 0.6～1.0 mg/min intravenous drip afterwards in amiodaron group, other 28 cases who accepted propafenone 1.4～2.0 mg/kg vein injection, and 0.28 mg/min intravenous drip afterwards in propafenone group.If propafenone was not effective, the cases in propafenone group were given amidoaron. ResultsThe successful reversion rate was 86.7% (26/30) in amidoaron group while 57.1% (16/28) in propafenone group(P<0.05). The mean time of recovering was (101±95) min (6～508 min) in amidoaron group, while (172±148) min (11～608 min) in propafenone group(P<0.05). ConclusionIt is more rapid and effective of amidoaron on the cardioversion of paroxysmal auricular fibrillation than propafenone is.

Key words: auricular fibrillation, amiodaron, propafenone, cardioversion