《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (08): 706-707.

• 临床研究 • 上一篇    下一篇

骨髓干细胞移植治疗骨不连及骨缺损临床研究

袁进国1,2; 周志玲3; 刘英飞3; 朱振安4   

  1. 1.解放军251医院急诊科,河北张家口市 175000;2.康保县医院外科,河北康保县 076650;3.河北北方学院附属第二医院骨外科,河北张家口市 075000;4.上海第二医科大学附属第九医院骨外科,上海市 200011
  • 收稿日期:2006-04-12 出版日期:2006-08-01 发布日期:2006-08-01

Study of Marrow Stem Cell Transplant for Treatment of Bone Nonunion and Bone Defection

YUAN Jin-guo, ZHOU Zhi-ling, LIU Ying-fei, et al   

  1. The251th Hospital of PLA, Zhangjiakou 075000, Hebei, China
  • Received:2006-04-12 Published:2006-08-01 Online:2006-08-01

PDF (PC)

被引次数

7

摘要： 目的观察自体骨髓干细胞移植治疗骨不连及骨缺损的疗效。方法140例患者随机分为自体髂骨移植组(A组)及自体骨髓干细胞移植组(B组)各70例,均行手术治疗,并行简单有效的内外固定。结果术后平均愈合时间A组为(7.0±2.0)个月,B组为(5.0±1.5)个月,两组间有显著性差异(P<0.05);治疗期间患者无明显不良反应。结论自体骨髓干细胞移植较传统植骨治疗骨不连及骨缺损疗程短、疗效好,无不良反应。

关键词: 骨髓干细胞, 骨髓移植, 骨不连, 骨缺损

Abstract: ObjectiveTo observe the curative effect of marrow stem cell transplant on bone nonunion and bone defection.Methods140 patients were randomly divided into the group A (with auto-iliac bone transplant) and group B (with auto-marrow stem cell transplant). There were 70 cases in each group. All patients in two groups were treated by operation and inside and outside fixation.ResultsAfter treatment, the average cicatrization time of group A was (7.0±2.0) months, that of group B was (5.0±1.5) months, there was a significant difference between two groups( P<0.05). There were no obvious adverse reactions found during the treatment period.ConclusionCompared with the traditional bone grafting, treating bone nonunion and bone defection by auto-marrow stem cell transplant has obvious superiority with better curative effect, short course and no adverse reactions.

Key words: marrow stem cell, marrow transplant, bone nonunion, bone defection