《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (05): 471-472.

• 临床研究 • 上一篇    下一篇

肾动脉成形术对肾静脉肾素活性和血管紧张素的影响

李晓斌; 任艺虹; 盖鲁粤   

  1. 解放军总医院心内科,北京市 100853
  • 收稿日期:2006-11-29 出版日期:2007-05-01 发布日期:2007-05-01

Effet of the Renal Artery Angioplasty on Level of Renin and Angiotensin in Renal Vein

LI Xiao-bin, REN Yi-hong, GAI Lu-yue   

  1. Department of Cardiology, the General Hospital of PLA, Beijing 100853, China
  • Received:2006-11-29 Published:2007-05-01 Online:2007-05-01

PDF (PC)

摘要： 目的探讨血管内治疗术对伴粥样硬化性肾动脉狭窄的高血压患者的治疗机制。方法98例患者肾动脉造影后根据管腔狭窄程度分为治疗组(狭窄≥70%)、狭窄组(狭窄50%～70%)和对照组(狭窄<50%)。比较各组患者术前、术后血压和肌酐的变化和术后即刻肾静脉肾素和血管紧张素活性的变化。结果治疗组术后即刻肾素和血管紧张素明显降低(P<0.01),与对照组无显著性差显;治疗后1个月血压和血肌酐下降(P<0.05)。结论肾动脉成形术能够降低肾动脉狭窄患者即刻肾静脉肾素活性和血管紧张素水平。

关键词: 肾动脉狭窄, 动脉粥样硬化, 血管成形术, 肾素, 血管紧张素, 高血压

Abstract: Objective To explore the mechanism of the renal artery angioplasty applied in hypertension with renal atherosclerosis. Methods Acording to the result of the renal artery angiography, 98 patients were divided to 3 groups. The renin activity and the angiotensin in the therapy groups were measured before and after the angioplasty and the datas were compared among 3 groups. Results After the angioplasty, the renin activity and the angiotensin significantly decreased in the therapy groups (P<0.01). The blood pressure and the creatinine decresed a month later. Conclusion The renal angioplasty can decrease the blood pressure and instantly decrease the renin activity and the angiotensin of the renal vein in hypertension with renal atherosclerosis.

Key words: renal artery stenosis, atherosclerosis, angioplasty, renin, angiotensin, hypertension