《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (12): 1168-1170.

• 临床研究 • 上一篇    下一篇

高分辨CT在慢性阻塞性肺疾病临床评价中的作用

赵红梅1,2; 聂秀红3a; 格崤3b; 魏兵3a; 李成儒3b; 任魁3a   

  1. 1.中国康复研究中心北京博爱医院内科,北京市 100068;2.首都医科大学康复医学院北京市,北京市 100068;3.首都医科大学宣武医院a.呼吸内科;b.放射科,北京市 100053
  • 收稿日期:2007-06-25 出版日期:2007-12-01 发布日期:2007-12-01

Role of High-resolution Computed Tomography in Evaluation for Patients with Chronic Obstructive Pulmonary Diseases

ZHAO Hong-mei, NIE Xiu-hong, GE Yao, et al   

  1. The Department of Internal Medicine, Beijing Charity Hospital, China Rehabilitation Research Center, Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
  • Received:2007-06-25 Published:2007-12-01 Online:2007-12-01

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被引次数

2

摘要： 目的探讨高分辨CT(HRCT)肺功能成像在慢性阻塞性肺疾病(COPD)临床评价中的作用,及其与BODE评分之间的相互关系。方法对32例稳定期COPD患者、22例正常对照进行肺功能检查、肺CT检查,比较HRCT的肺功能成像参数与PFT检查、BODE指数之间的相关性。结果COPD组的深吸气容积(Vin)与正常对照组的差异无统计学意义(P>0.05),深呼气容积(Vex)及像素指数均明显高于正常对照组(P<0.01),Vex和Vin均与FEV1/FVC呈负相关(P<0.05),与FEV1占预计值%无相关性(P>0.05),与BODE评分亦无相关性(P>0.05),Vex/Vin与BODE评分呈正相关(P<0.05)与FEV1/FVC无相关性(P>0.05),呼气相像素指数(PI910ex)与FEV1占预计值%及FEV1/FVC均呈负相关(P<0.05),PI910ex与BODE评分呈明显正相关(P<0.01),吸气相像素指数(PI960in)与FEV1占预计值%、FEV1/FVC、BODE评分均无相关性(P>0.05)。结论CT肺功能测定,尤其在深呼气相,以-910Hu做为界定肺气肿与正常肺组织的阈值时的像素指数(PI910in)与FEV1占预计值%、FEV1/FVC及BODE评分呈相关关系。

关键词: 慢性阻塞性肺疾病, 高分辨计算机断层扫描, 肺功能检查, BODE指数

Abstract: Objective To investigate the evaluation of high-resolution computed tomography (HRCT) in patients with chronic obstructive pulmonary diseases (COPD), and the relationship with the pulmonary function test and BODE index.Methods 32 COPD patients and 22 normal controls were examined by pulmonary function test (PFT) and HRCT. The data of two groups were compared.Results The volume and pixel index (PI) in forced expiration were higher in the COPD group than those in the control group ( P<0.01), but there was no significant difference in Vin between two groups ( P>0.05). In the COPD group, Vex and Vin were negatively correlated with FEV1/FVC ( P<0.05) respectively. There were no correlation between Vin, Vex and FEV1% pre in the COPD patients ( P>0.05) respectively. Vin and Vex were not correlated with BODE index (all P>0.05) respectively. The ratio of Vex/Vin was positively correlated with BODE index ( P<0.05), and not correlated with FEV1/FVC ( P>0.05). PI910ex was positively correlated with BODE index ( P<0.01), and negatively correlated with FEV1%pre, FEV1/FVC (all P<0.05) respectively.Conclusion The pulmonary function of COPD patients can be evaluated by HRCT, especially by PI910ex.

Key words: chronic obstructive pulmonary diseases, high-resolution computed tomography (HRCT) scanning, pulmonary function test, BODE index