《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (02): 171-172.

• 临床研究 • 上一篇    下一篇

14例心脏淀粉样变性的临床特点分析

杨泉; 盖鲁粤   

  1. 解放军总医院心内科,北京市 100853
  • 收稿日期:2007-07-10 出版日期:2008-02-01 发布日期:2008-02-01

Clinical Characteristics of 14 Patients with Cardiac Amyloidosis

YANG Quan, GAI Lu-yue.   

  1. The General Hospital of PLA, Beijing 100853, China
  • Received:2007-07-10 Published:2008-02-01 Online:2008-02-01

摘要: 目的探讨心脏淀粉样变性的临床特点。方法对14例心脏淀粉样变性患者进行超声心动图和心电图检查,结合病理检查分析心脏淀粉样变性的临床特点。结果心脏超声心动图表现为患者左、右心房增大,心室肥厚,心腔正常;心电图表现为肢体导联低电压,心电图电压(SV5+RV1)与左心室横截面积CSA比值均明显小于1.5;心外活检表现为刚果红染色阳性,且大部分患者合并肾脏、皮肤及消化系统损害。结论对临床心力衰竭的患者,如果具有心肌肥厚但心电图又表现为肢体导联低电压时应考虑心脏淀粉样变性的可能性,需进一步做病理活检加以证实。心电图电压(SV5+RV1)与左室横截面积CSA比值可能成为心脏淀粉样变性的一项有效的筛选指标。

关键词: 淀粉样变性病, 超声心动图, 心电图

Abstract: Objective To analyze the clinical characteristics of patients with cardiac amyloidosis.Methods The clinical data of 14 patients with cardiac amyloidosis were retrospectively analysed.Results The patients with cardiac amyloidosis had characteristics of large atriums and hypertrophic ventricular walls in echocardiography.And they also had low limb lead voltage in ECG.The ratio of(SV5+RV1)and left ventricle crossing area of all patients were obviously lower than 1.5.Biopsy behaved staining of congo red.And most patients had renal,dermatic and gastrointestinal involvements.Conclusion The patients of cardiac dysfunction with the characteristics of restrictive cardiomyopathy in echocardiogram and feature of low limb lead voltage in ECG,have the possibility of cardiac amyloidosis and need to prove it through biopsy.(SV5+RV1)/CSA may be a promising method for screening cardiac amyloid.

Key words: cardiac amyloidosis, echocardiogram, electrocardiogram