《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (06): 513-514.

• 专题 • 上一篇    下一篇

氟比洛芬酯复合芬太尼用于颅脑手术后患者自控镇痛的临床观察

程灏; 肖峰; 金旭; 韩如泉   

  1. 首都医科大学附属北京天坛医院麻醉疼痛科,北京市 100050
  • 收稿日期:2008-05-18 出版日期:2008-06-01 发布日期:2008-06-01

Effect of Flurbiprofen Axetil Combined with Fentanyl in Postoperative Patient-controlled Analgesia after Craniotomy

CHENG Hao,XIAO Feng, JIN Xu, et al   

  1. The Department of Anesthesiology, BeijingTiantan Hospital, CapitalMedical University, Beijing 100050, China
  • Received:2008-05-18 Published:2008-06-01 Online:2008-06-01

PDF (PC)

被引次数

9

摘要： 目的观察氟比洛芬酯复合芬太尼用于颅脑手术后患者自控镇痛的效果和副作用。方法60例神经外科择期开颅手术患者随机分为研究组和对照组,各30例,分别采用氟比洛芬酯复合芬太尼和单独芬太尼行术后镇痛。记录术后4h、次日晨、术后24h疼痛评分(VAS)、镇静程度评分(SS)及不良反应。结果两组患者的镇痛效果差异无统计学意义(P>0.05),研究组镇静程度低于对照组(P<0.05),恶心、呕吐等不良反应发生率亦低于对照组(P<0.05)。结论氟比洛芬酯复合芬太尼用于颅脑手术后镇痛,可以减少芬太尼用量和芬太尼引起的不良反应,提高镇痛质量。

关键词: 氟比洛芬酯, 芬太尼, 患者自控镇痛

Abstract: Objective To investigate the effect and side effects of flurbiprofen axetil combined with fentanyl in postoperative patient-controlled analgesia (PCA) after craniotomy.Methods 60 patients undergoing scheduled craniotomy were randomly divided into the treatment group and control group with 30 cases in each group, and received flurbiprofen axetil combined with fentanyl and only fentanyl respectively in PCA after craniotomy. The visual analogue scale (VAS), sedation score (SS) and the side effects were evaluated in 24 h after craniotomy.Results There was no significant difference in VAS between the two groups ( P>0.05). The SS, side effects such as nausea and vomiting in the treatment group were significantly less than that in the control group ( P<0.05).Conclusion Flurbiprofen axetil combined with fentanyl in PCA can reduce the side effects of fentanyl and offers overall favorable analgesic responses.

Key words: flurbiprofen, fentanyl, patient-controlled analgesia