《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (06): 539-541.

• 综述 • 上一篇    下一篇

非人灵长类动物局灶性脑缺血模型的制备及神经功能评价的研究

王强1,2; 张通1,2   

  1. 1.首都医科大学康复医学院,北京市 100068;2.中国康复研究中心北京博爱医院神经康复科,北京市 100068
  • 收稿日期:2007-11-22 出版日期:2008-06-01 发布日期:2008-06-01

Advance in Research of Establishment and Neurological Behavioral Assessment of Non-human Primate Local Cerebral Ischemic Model (review)

WANG Qiang, ZHANG Tong   

  1. The Department of Neurorehabilitation, Capital Medical University School of Rehabilitation Medicine, Beijing Charity Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2007-11-22 Published:2008-06-01 Online:2008-06-01

摘要: 非人灵长类动物的神经机能和脑血管解剖与人类非常相似,利用非人灵长类动物建立的脑缺血模型是研究脑血管疾病损伤机制和防治措施常用的工具。笔者就非人灵长类动物局灶性脑缺血模型制备方法及其神经、行为功能的评价方法作一综述。

关键词: 非人灵长类, 脑缺血模型, 神经行为功能评价, 综述

Abstract: The neurologic function and cerebral vascular anatomy of non-human primate are closely resemble to those of human, so non-human primate cerebral ischemic model is a particularly useful tool in studying the damage mechanism and therapy intervention of cerebrovascular disorder. The authors reviewed the establishment method and neurological behavioral assessmental method of non-human primate cerebral ischemic model.

Key words: non-human primate, cerebral ischemic model, neurological behavioral assessment, review