《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (08): 765-766.

• 临床研究 • 上一篇    下一篇

小儿脑瘫危险因素分析析

张传东1; 秦浩2; 王福民3; 张新民1; 吴建元1   

  1. 1.山东省潍坊市社会福利院,山东潍坊市 261200;2.潍坊医学院预防医学系,山东潍坊市 261042;3.山东省潍坊市妇幼保健院,山东潍坊市 261011
  • 收稿日期:2008-02-21 出版日期:2008-08-01 发布日期:2008-08-01

Risk Factors of Childhood Cerebral Palsy

ZHANG Chuan-dong, QIN Hao, WANG Fu-min, et al   

  1. Welfare Home of Weifang,Weifang 261200, Shandong, China
  • Received:2008-02-21 Published:2008-08-01 Online:2008-08-01

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摘要： 目的探讨小儿脑瘫的发病危险因素。方法对100例脑瘫患儿及200例对照进行1∶2匹配病例对照研究,所获数据采用Logistic回归分析。结果单因素分析显示,出生医院级别、父母亲文化程度、早产、新生儿窒息、ABO溶血、低体重、缺血缺氧性脑病(HIE)、核黄疸等与小儿脑瘫的发生有关联;多因素分析显示,出生医院级别、父亲文化程度、早产、新生儿窒息、ABO溶血、低体重、HIE为小儿脑瘫发病的主要危险因素。结论小儿脑瘫发病的相关危险因素是多方面的。

关键词: 脑性瘫痪, 危险因素, 调查

Abstract: Objective To investigate the risk factors of cerebral palsy(CP)in children.Methods 1∶2 matched case-control study was carried out in 100 CP children and 200 controls individually matched for sex and age were selected for each case.The data were analyzed with Logistic regression.Results 9 risk factors were suggested from univariate analysis,namely hospital level,educational level of mother and father,premature birth,neonatal asphyxia,ABO hemolysis,lower birth weight,hypoxic-ischemic encephalopathy(HIE)and kernicterus.The risk factors confirmed by multivariate analysis were hospital level,educational level of father,premature birth,neonatal asphyxia,ABO hemolysis,lower birth weight and HIE.Conclusion Relevant risk factors of CP are various.

Key words: cerebral palsy, risk factors, investigation