《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (08): 771-773.

• 临床研究 • 上一篇    下一篇

庆大霉素复合罗哌卡因或利多卡因复合曲安缩松治疗三叉神经痛的早期疗效

孟岚; 王保国; 罗芳; 申颖   

  1. 首都医科大学附属北京天坛医院麻醉疼痛科,北京市 100050
  • 收稿日期:2008-03-24 出版日期:2008-08-01 发布日期:2008-08-01

Effects of Gentamycin Combined with Ropivacaine and Lidocaine Combined with Triamcinolone on Trigeminal Neuralgia

MENG Lan,WANG Bao-guo, LUO Fang, et al   

  1. The Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2008-03-24 Published:2008-08-01 Online:2008-08-01

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摘要： 目的比较庆大霉素复合罗哌卡因与曲安缩松治疗三叉神经痛的早期疗效。方法90例三叉神经痛患者随机分为罗哌卡因组和曲安缩松组,分别用庆大霉素复合罗哌卡因或曲安缩松行外周神经阻滞。比较治疗前、治疗后1d、3d、1周、2周、1个月、2个月和3个月时的治疗效果,以及两组患者治疗前后卡马西平用量的变化。结果治疗后,两组患者各时间点数字评分(NRS)均较治疗前降低,罗哌卡因组治疗后1d、1个月、2个月及3个月时的NRS值均优于曲安缩松组。结论庆大霉素复合罗哌卡因治疗三叉神经痛效果较好;曲安缩松对三叉神经痛亦有一定效果,可用于病情不太严重的患者。

关键词: 三叉神经痛, 庆大霉素, 罗哌卡因, 曲安缩松, 神经阻滞

Abstract: Objective To compare the early therapeutic effects of gentamycin combined with ropivacaine and triamcinolone on trigminal neuralgia.Methods Ninety patients with trigeminal neuralgia were randomly divided into the ropivacaine group and triamcinolone group.The received nerve block peripherally was performed with gentamycin combined with ropivacaine(in the ropivacaine group)or triamcinolone(in the triamcinolone group)respectively.The parameters included pain intensity before and 1 d,3 d,1 week,2 weeks,1 month,2 months and 3 months after treatment,pain relief rate and dosage of carbamazepine of two groups were compared.Results The pain intensity in all the groups decreased at each time point.The value of numeric rating scale(NRS)in the ropivacaine group was significantly less than that in the triamcinolone group at 1 d,1 month,2 months and 3 months.Conclusion Gentamycin combined with ropivacaine is more suitable for trigeminal neuralgia than triamcinolone.

Key words: trigeminal neuralgia, gentamycin, ropivacaine, triamcinolone, nerve block