《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (09): 831-832.

• 专题 • 上一篇    下一篇

脑卒中患者卒中相关性感染临床分析

陈军; 于光莉; 徐玉新   

  1. 清华大学玉泉医院内科,北京市 100049
  • 收稿日期:2007-06-17 出版日期:2008-09-01 发布日期:2008-09-01

Stroke-associated Infection:382 Serial Case Study

CHEN Jun ,YU Guang-li,XU Yu-xin   

  1. Department of Inter-Medicine, Yuquan Hospital of Tsinghua University, Beijing 100049, China
  • Received:2007-06-17 Published:2008-09-01 Online:2008-09-01

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摘要： 目的探讨脑卒中患者卒中相关性感染的发病率、危险因素及其对预后的影响。方法回顾性分析382例急性脑卒中患者的有关临床资料。结果并发卒中相关性感染112例(29.3%);感染部位以下呼吸道(63.0%)和泌尿道(28.4%)最常见;致病菌居前3位的分别是大肠埃希氏菌、凝固酶阴性葡萄球菌及链球菌;高龄、糖尿病、病情重、预防性应用抗菌药物及侵袭性操作等与卒中相关性感染相关。并发卒中相关性感染患者病死率升高(12/112 vs 5/270,χ2=14.622,P<0.01)。结论卒中相关性感染是多种因素作用的结果。控制卒中相关性感染可有效提高脑卒中治疗的成功率。

关键词: 脑卒中, 卒中相关性感染, 危险因素, 病死率

Abstract: Objective To study the incidence,risk factors and prognosis of stroke-associated infection(SAI) in acute stroke patients.Methods 382 serial acute cerebral stroke patients were retrospectively surveyed.Results The incidence of SAI was 29.3% in all cases,mainly involved lower respiratory tract(63.0%) and urinary tract(28.4%).Escherichia coli,Coagulase negative staph and Streptococcus viridans were the main pathogenic organisms.Developments of SAI were closely related with aging,diabetes mellitus,the application of antimicrobial agents and invasive procedure.The mortality was 10.7%(12/112) in the cases with SAI,but 1.9%(5/270) in the cases without SAI.Conclusion SAI is caused by various factors in acute stroke patients.Controlling SAI can help to succeed in treating stroke.

Key words: stroke, stroke-associated infection(SAI), risk factors, mortality