《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (10): 956-957.

• 临床研究 • 上一篇    下一篇

应用公式计算A型肉毒毒素剂量缓解脑瘫小腿三头肌痉挛的对照研究

刘建军1,2; 纪树荣1,2; 胡莹媛1,2; 吴卫红1,2; 李燕春1,2; 陆华宝1,2; 张雁1,2   

  1. 1.首都医科大学康复医学院,北京市 100068;2.中国康复研究中心北京博爱医院,北京市 100068
  • 收稿日期:2007-07-19 出版日期:2008-10-01 发布日期:2008-10-01

Releasing Spasticity of Triceps Surae Muscle of Children with Spastic Cerebral Palsy by Botulinum Toxic A Block with Dose Calculated According to Certain Formula

LIU Jian-jun, JI Shu-rong, HU Ying-yuan, et al   

  1. CapitalMedical University School of Rehabilitation Medicine, Beijing Charity Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2007-07-19 Published:2008-10-01 Online:2008-10-01

PDF (PC)

被引次数

1

摘要： 目的探讨应用公式计算A型肉毒毒素(BTX-A)使用剂量是否可以提高疗效、延长疗效持续时间。方法15例脑瘫患儿为试验组,按照公式计算BTX-A使用剂量进行缓解痉挛治疗。58例患儿作为对照组,按常规方法确定BTX-A剂量。结果治疗后,试验组患儿下肢功能提高的幅度大于对照组(P<0.05),疗效持续时间显著长于对照组(P<0.001)。结论应用公式计算BTX-A剂量可以提高疗效,延长疗效持续时间。

关键词: 脑性瘫痪, 痉挛, A型肉毒毒素, 神经阻滞, 剂量

Abstract: Objective To investigate whether the curative effect of Botulinum Toxic A(BTX-A) block increased and prolonged when the dose calculated according to certain formula.Methods 15 children with cerebral palsy(CP) were appointed as the trial group and the dose of BTX-A was calculated according to the designed formula.The other 58 CP children were appointed as the control group and the BTX-A dose was determined by routine method.Results After treatment,the motor function of the children in trial group was superior to that in the control group(P<0.05) and the duration of therapeutic effect of the trial group was significantly longer than the control group(P<0.001).Conclusion BTX-A dose calculated according to the formula can increase effect and prolong the duration.

Key words: cerebral palsy, spasticity, botulinum toxic A, nerve block, dose