《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (01): 58-59.

• 临床研究 • 上一篇    下一篇

CD62P与急性脑梗死的相关性

蒙绪卿   

  1. 海南省人民医院康复中心，海南海口市 570311
  • 收稿日期:2008-03-25 修回日期:2008-04-18 出版日期:2009-01-01 发布日期:2009-01-01

Relationship between CD62P and Acute Cerebral Infarction

MENG Xu-qing   

  1. Rehabilitation Center, the People's Hospital of Hainan, Haikou 570311, Hainan, China
  • Received:2008-03-25 Revised:2008-04-18 Published:2009-01-01 Online:2009-01-01

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摘要： 目的 观察急性血栓性脑梗死（ATCI）和急性心源性脑栓塞(ACCE)患者CD62P的表达水平。方法 利用流式细胞仪测定35例ATCI患者、30例ACCE患者和33例正常对照组血液样本CD62P的表达水平。结果 与对照组相比，ATCI组和ACCE组CD62P均无升高(F=1.12，F=1.59,均P>0.05)；ATCI组和ACCE组间CD62P表达水平也无显著性差异(F=1.12，P>0.05)。结论 CD62P虽然是一种血小板活化标志物，但不论在急性血栓性脑梗死还急性心源性脑栓塞发病过程中，表达并无明显升高。

关键词: CD62P, 急性血栓性脑梗死, 急性心源性脑栓塞, 流式细胞仪

Abstract: Objective To investigate the levels of CD62P expression on patients with acute thrombotic cerebral infarction （ATCI） or acute cardiogenic cerebral embolism (ACCE). Methods The levels of CD62P expression were detected with flow cytometry (FCM) in the blood of 35 patients with ATCI, 30 patients with ACCE, and 33 healthy controls. Results Comparing with the controls, the levels of CD62P expression on patients did not increase both in the ATCI group and the ACCE group. (F=1.12, F=1.59；P>0.05). Furthermore, there wasn't significant difference in the expressions of CD62P between the ATCI group and the ACCE group. Conclusion The expressions of CD62P do not increase on the patients with ATCI and ACCE, although it is one of the markers of platelets activation.

Key words: CD62P, acute thrombotic cerebral infarction, acute cardiogenic cerebral embolism, flow cytometry