《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (02): 114-116.

• 专题 • 上一篇    下一篇

脊髓损伤后中枢性疼痛的研究

刘舒佳1,2;李建军1,2;高峰1,2   

  1. 1. 首都医科大学康复医学院,北京市 100068;2. 中国康复研究中心,北京市100068
  • 收稿日期:2008-10-15 出版日期:2009-02-01 发布日期:2009-02-01
  • 通讯作者: 李建军

Central Pain Following Spinal Cord Iinjury (review)

LIU Shu-jia, LI Jian-jun, GAO Feng   

  1. Capital Medical University School of Rehabilitation Medicine, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2008-10-15 Published:2009-02-01 Online:2009-02-01

摘要: 中枢性疼痛是脊髓损伤后常见并发症之一,致病机制目前尚不明确,但对患者的日常生活可造成严重影响。脊髓本身的损伤、神经结构的破坏以及继发的病理改变都有造成中枢性疼痛的可能,其深层机制均与脊髓中枢兴奋性过高相关。基于这一理论,相应的治疗方案已经应用于临床并取得不同程度的疗效。笔者就中枢性疼痛的发生机制以及治疗措施的最新进展做一综述。

关键词: 脊髓损伤, 中枢性疼痛, 综述

Abstract: Central pain (CP) following spinal cord injury (SCI) challenges the health care community. A number of pain syndromes associated with SCI are based on the nature of the lesion, neurological structure damage and secondary pathophysiological changes. The hyperresponsiveness of neurons following SCI is the key factor of the mechanisms of CP. And several treatments have received some effects. So it is very important to study the mechanisms and therapies of CP.

Key words: spinal cord injury, central pain, review