《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (03): 272-273.

• 临床研究 • 上一篇    下一篇

假瘤样脱髓鞘病的临床特点与治疗

杨海波;齐巍;张伟;张懋植   

  1. 首都医科大学附属北京天坛医院神经外科，北京市 100050
  • 收稿日期:2008-12-22 出版日期:2009-03-01 发布日期:2009-03-01
  • 通讯作者: 张懋植

Clinical Characteristics and Treatment of Pseudotumor Forms of Demyelinating Diseases: 21 Cases Report

YANG Hai-bo, QI Wei, ZHANG Wei, et al   

  1. Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2008-12-22 Published:2009-03-01 Online:2009-03-01

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摘要： 目的 探讨假瘤样脱髓鞘病的临床特点和治疗。方法 对21例经组织病理学证实的假瘤样脱髓鞘病患者进行回顾性分析。结果 主要临床表现包括偏瘫合并偏身感觉障碍，颅内压增高，癫痫等。5例发病前有明确的感冒和疫苗接种史。16例行显微手术治疗，5例取活组织检查。皮质类固醇激素治疗后症状均得到明显改善。随访时间6～70个月(平均37个月)。4例（19%）复发，死亡1例。结论 假瘤样脱髓鞘病的临床特点与颅内肿瘤类似，影像学具有一定的特征性表现。正确的诊断结合类固醇激素治疗可获得满意疗效。

关键词: 假瘤样脱髓鞘病, 临床表现, 治疗, 预后

Abstract: Objective To discuss the clinical characteristics, treatment and prognosis of pseudotumor forms of demyelinating diseases. Methods 21 patients with pseudotumor forms of demyelinating diseases diagnosed pathologically were analyzed retrospectively. Results 16 cases were operated on. The lesions were established through biopsy in other 5 patients. All the patients improved significantly after corticosteroid therapy. 4 patients relapsed after treatment, and 1 patient died. Conclusion The feature of pseudotumor forms of demyelinating disease is similar to some kinds of intracranial tumors, however it presents some radiological characteristics. Diagnostic corticoid therapy may be helpful to draw a diagnosis.

Key words: pseudotumor forms of demyelinating diseases, feature, treatment, prognosis