《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (04): 372-373.

• 临床研究 • 上一篇    下一篇

术中应用甲基强的松龙对脊髓型颈椎病疗效的影响

袁亮;李靖年;张彦   

  1. 大连医科大学第二医院脊柱外科，辽宁大连市 116023
  • 收稿日期:2009-01-06 出版日期:2009-04-01 发布日期:2009-04-01

Effect of Methylprednisolone on Surgical Treatment of Cervical Spondylotic Myelopathy

YUAN Liang, LI Jing-nian, ZHANG Yan   

  1. The Department of Spine Surgery, the Second Hospital of Dalian Medical University, Dalian 116023, Liaoning, China
  • Received:2009-01-06 Published:2009-04-01 Online:2009-04-01

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被引次数

5

摘要： 目的 探讨术中应用甲基强的松龙(MP)对脊髓型颈椎病患者脊髓减压术后神经功能恢复的影响。方法 114例行颈椎前路减压治疗脊髓型颈椎病患者分为MP组和对照组，每组57例。MP组于脊髓减压前30 min给予MP 20 mg/kg体重快速静滴；对照组仅行前路减压手术。观察两组患者术后的并发症。术前及术后1 d、2周、6个月分别用美国脊髓损伤协会（ASIA）评分标准评定患者的神经功能。结果 MP组在术后1 d、2周和6个月时的脊髓功能康复情况好于对照组（ P＜0.05），并发症发生率两组患者间的差异无显著性意义（ P＞0.05）。结论 术中应用MP能促进脊髓型颈椎病患者脊髓减压术后神经功能的康复。

关键词: 甲基强的松龙, 脊髓型颈椎病, 神经功能

Abstract: Objective To investigate the effects of methylprednisolone (MP) on the recovery of postoperative neurological functions due to cervical spondylotic myelopathy.Methods 114 patients with cervical spondylotic myelopathy were divided into the MP group and the control group with 57 cases in each group. The cases of the MP group were treated with MP (20 mg/kg, iv) 30 min prior to the decompression. Those of the control group underwent anterior decompression only. The complications of patients in two groups were compared. The neurological functions of all patients were graded according the ASIA score system preoperatively and at 1st day, 2nd week and 6th month postoperatively.Results Compared with the control group, the neurological functions of the cases in the MP group improved significantly after operation ( P＜0.05).Conclusion For patients with cervical spondylotic myelopathy, MP used during operation can improve postoperative neurological function recovery.

Key words: methylprednisolone, cervical spondylotic myelopathy, neurological function