《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (05): 455-457.

• 临床研究 • 上一篇    下一篇

脑梗死后焦虑抑郁共病患者的临床特征

王宁群;李宗信;黄小波;陈文强   

  1. 首都医科大学宣武医院中医科，北京市 100053
  • 收稿日期:2009-01-13 修回日期:2009-02-17 出版日期:2009-05-01 发布日期:2009-05-01

Clinical Characteristics of Comorbid Anxiety and Depression after Cerebral Infarction

WANG Ning-qun, LI Zong-xin, HUANG Xiao-bo, et al   

  1. Xuanwu Hospital, Capital Medical University, Beijing 100053，China
  • Received:2009-01-13 Revised:2009-02-17 Published:2009-05-01 Online:2009-05-01

PDF (PC)

被引次数

48

摘要： 目的 研究脑梗死急性期焦虑抑郁共病患者的临床特征。方法 将符合研究标准的急性期脑梗死病例分为焦虑抑郁共病（PSCAD）组84例和对照组121例。比较两组患者吸烟、饮酒、文化程度、工作生活压力、日常锻炼频度等相关因素的差异，汉密顿焦虑量表(HAMA)和汉密顿抑郁量表(HAMD)总分、各因子分及各项症状分，Barthel指数、简易精神状态检查（MMSE）评分及血管超声情况。结果 两组患者吸烟、饮酒、文化程度、工作生活压力、日常锻炼情况、颈动脉及颅内动脉病变程度均无显著性差异。PSCAD组HAMA、HAMD总分及各因子分均高于对照组（P<0.05）。PSCAD组的焦虑症状以焦虑心境、抑郁心境、紧张、失眠、认知功能障碍、自主神经系统症状较为突出，抑郁症状以精神性焦虑、躯体性焦虑、绝望感、负罪感、工作和兴趣障碍较为突出。PSCAD组MMSE总分、Barthel指数评分低于对照组（P<0.05）。结论 脑梗死急性期焦虑抑郁共病患者临床表现以精神症状为主，伴见躯体症状，其认知功能较差，日常生活能力下降。

关键词: 脑梗死, 焦虑抑郁共病, 认知, 日常生活能力

Abstract: Objective To determine the clinical characteristics of comorbid anxiety and depression after cerebral infarction. Methods All the patients enrolled were divided into post-stroke comorbid anxiety and depression (PSCAD) group (84 cases) and the control group (121 cases). Their condition of smoke, alcohol intake, education background, carotid plaque and brain blood vessels were investigated, and they were evaluated with Hamilton Anxiety Scale (HAMA), Hamilton Depressive Scale (HAMD), Barthel index, and Mini-Mental State Examination (MMSE). Results There was not significant difference in condition of smoke, alcohol intake, education background, carotid plaque and brain blood vessels between these groups （P＞0.05）, but were in total scores and all the factors scores of HAMA and HAMD （P＜0.05）. PSCAD group showed more obvious anxious mood, depressive mood, tension, insomnia, cognitive impairment and autonomic nervous symptoms. Psycho-anxiety, soma-anxiety, despair, guiltiness, decreased interest were also more significant in the PSCAD group. The scores of MMSE and Barthel index were also impaired. Conclusion The cognitive function and daily living ability are worse in the patients with PSCAD. The prominent symptoms includes: anxious mood, depressive mood, tension, insomnia, cognitive impairment, autonomic nervous symptoms, soma-anxiety, despair, guiltiness, decreased interest.

Key words: cerebral infarction, comorbid anxiety and depression, cognition, ability of daily living