《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (06): 585-586.

• 临床研究 • 上一篇    下一篇

氟西汀对脑梗死后抑郁患者神经功能缺损及日常生活能力的影响

范录平;杨晓国;林一均;陈晓顶;张有超   

  1. 温州市第三人民医院神经内科，浙江温州市 325000
  • 收稿日期:2009-03-23 出版日期:2009-06-01 发布日期:2009-06-01

Effect of Fluoxetine on Depression Neurologic Impairment and Activity of Daily Living after Cerebral Infarction

FAN Lu-ping, YANG Xiao-guo, LIN Yi-jun, et al   

  1. Third People's Hospital of Wenzhou, Wenzhou 325000, Zhejiang, China
  • Received:2009-03-23 Published:2009-06-01 Online:2009-06-01

PDF (PC)

被引次数

33

摘要： 目的 观察氟西汀对脑梗死后抑郁患者神经功能缺损及日常生活能力的影响。方法 临床选取急性脑梗死后抑郁患者80例，随机将患者分为治疗组(氟西汀)和对照组各40例，治疗前后分别用改良爱丁堡-斯堪的那维亚脑卒中评分量表(MESSS)、汉密顿抑郁量表（HAMD）和改良巴氏指数量表(MBI)进行评分，评定氟西汀的治疗作用。结果 治疗前两组间HAMD、MESSS和MBI无显著性差异（P＞0.05），治疗后6周两组间HAMD、MESSS和MBI均有显著性差异（P＜0.01）。结论 氟西汀能缓解急性脑梗死患者的抑郁症状，促进急性脑梗死患者的神经功能恢复，提高患者的日常生活能力。

关键词: 氟西汀, 脑梗死, 抑郁, 日常生活能力

Abstract: Objective To observe the effect of fluoxetine on the depression neurologic impairment and activity of daily living after cerebral infarction.Methods 80 patients with acute cerebral infarction following depression were randomly divided into treatment group and control group, 40 cases in each group. Two groups were assessed with Modified Edinburgh-Scandinavia Stroke Scale(MESSS), Hamilton Depression Scale(HAMD) and Modified Barthel Index(MBI) before and after treatment.Results There were no significant difference between the two groups before treatment in HAMD, MESSS and MBI（P＞0.05）, while there were significantly different between the two groups in HAMD, MESSS and MBI 6 weeks after treatment（P＜0.01）. Conclusion Fluoxetine can alleviate depression of patients with acute cerebral infarction and improve the symptom of neurological function and the activity of daily living.

Key words: fluoxetine, cerebral infarction, depression, activity of daily living