《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (07): 652-653.

• 临床研究 • 上一篇    下一篇

颈动脉粥样硬化与脑梗死患者认知障碍及生存质量的关系

黄小波;李宗信;王宁群;陈文强   

  1. 首都医科大学宣武医院中医科，北京市 100053
  • 收稿日期:2009-02-01 修回日期:2009-05-19 出版日期:2009-07-01 发布日期:2009-07-01
  • 通讯作者: 王宁群

Relationship between Carotid Atherosclerosis and Cognitive Impairment or Quality of Life in Patients with Cerebral Infarction

Huang Xiao-bo,LI Zong-xin,WANG Ning-qun,et al   

  1. Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2009-02-01 Revised:2009-05-19 Published:2009-07-01 Online:2009-07-01

PDF (PC)

被引次数

11

摘要： 目的 探讨颈动脉粥样硬化（CAS）与脑梗死患者认知障碍、卒中特异性生存质量的关系。方法 将符合研究标准的首发脑梗死患者根据颈动脉超声情况分为轻中度CAS组和重度CAS组。运用简易智力状态试验(MMSE)、脑卒中影响量表(SIS)3.0版进行评定。结果 重度CAS患者MMSE注意力/计算力、语言理解和总分，SIS行动能力和手功能维度评分均低于轻中度CAS组（P<0.05）。结论 颈动脉粥样硬化程度对脑梗死患者认知功能和生存质量均有负面影响。

关键词: 颈动脉粥样硬化, 脑梗死, 认知障碍, 生存质量

Abstract: Objective To investigate the relationship between carotid atherosclerosis （CAS） and cognitive impairment, stroke-specific quality of life of patients with cerebral infarction. Methods Patients enrolled were divided into mild-to-moderate CAS group and severe CAS group after carotid ultrasound. They were assessed with Mini Mental State Examination (MMSE) and Stroke Impact Scale (SIS) Version 3.0. Results The scores of attention/calculation, comprehension, and total of MMSE, the mobile ability and hand function dimensions of SIS were all lower in severe CAS group than in mild-to-moderate CAS group （P<0.05）. Conclusion Carotid atherosclerosis may further impair the cognitive function and quality of life of cerebral infarction patients.

Key words: carotid atherosclerosis （CAS）, cerebral infarction, cognitive impairment, quality of life