《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (12): 1130-1132.

• 专题 • 上一篇    下一篇

高压氧结合小脑顶核刺激治疗慢性脑供血不足患者的脑血流及脑电图观察

王磊1a;贺谊1a;郑虎1a;王华1a;李厚成1b   

  1. 1.郧阳医学院附属太和医院,a.神经内科;b.高压氧室，湖北十堰市 442000
  • 收稿日期:2009-09-07 修回日期:2009-11-02 出版日期:2009-12-25 发布日期:2009-12-25
  • 通讯作者: 贺谊

Effects of Hyperbaric Oxygen Combined with Fastigial Nucleus Stimulation on Chronic Cerebral Circulation Insufficiency with Transcranial Doppler and Electroencephalography

WANG Lei,HE Yi,ZHENG Hu,et al   

  1. Department of Neurology, Taihe Hospital of Yunyang Medical College, Shiyan 442000, Hubei, China
  • Received:2009-09-07 Revised:2009-11-02 Published:2009-12-25 Online:2009-12-25

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被引次数

5

摘要： 目的 探讨高压氧结合小脑顶核刺激(FNS)对慢性脑供血不足（CCCI）患者脑血流及脑电的影响。方法 144例CCCI患者分为4组：高压氧+FNS组36例，FNS组36例，高压氧组36例，不接受以上治疗的36例为对照组。应用经颅多普勒超声（TCD）和脑电图（EEG）分别检测刺激前后大脑前、中、后动脉及椎动脉、基底动脉的血流速度及各频段脑电波（α、β、δ、θ波）变化。结果 各治疗组患者脑血流速度较对照组增高，α波增多，θ、δ波减少（P<0.05）；高压氧+FNS组疗效更优。结论 高压氧、FNS均可提高脑供血不足患者的脑血流量，两者合用可提高疗效。

关键词: 慢性脑供血不足（CCCI）, 高压氧(HBO), 小脑顶核刺激(FNS), 经颅多普勒超声（TCD）, 脑电图（EEG）

Abstract: Objective To observe the of changes of cerebral blood flow and electroencephalography in chronic cerebral circulation insufficiency (CCCI) treated with fastigial nucleus stimulation (FNS) and hyperbaric oxygen (HBO). Methods 144 cases of CCCI were divided into 4 groups: 36 cases were treated with FNS and HBO, 36 cases with FNS, 36 cases with HBO, 36 cases without any treatment as control group. The blood velocity of anterior, middle, posterior cerebral arteries, vertebral artery and basilar artery were measured with transcranial Doppler (TCD) and the brain waves （α, β, δ, θ） were recorded with electroencephalography (EEG) before and after the treatment. Results Compared with the control, the brain blood velocity and α wave increased in all the treatment groups, especially in the HBO+FNS group, while β, δ, θ waves decreased (P<0.05). Conclusion FNS and HBO can increase cerebral blood flow and improve the cerebral function respectively.

Key words: chronic cerebral circulation insufficiency, hyperbaric oxygen, fastigial nucleus stimulation, transcranial Doppler, electroencephalography