《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (11): 1060-1061.

• 论文 • 上一篇    下一篇

神经内外科连续3年脑脊液培养的菌群分布和耐药性分析

靳颖1a，马铁柱1b，吴玉秀1a，刘锦1a，韩海燕1a   

  1. 1.武警医学院附属医院，a.检验科;b.脑系科， 天津市 300162
  • 收稿日期:2010-07-29 修回日期:2010-09-20 出版日期:2010-11-25 发布日期:2010-11-25

Distribution and Resistance of Pathogens Isolated from Cerebrospinal Fluid: Result of Specimens in 3 Years

JIN Ying, MA Tie-zhu, WU Yu-xiu, et al   

  1. Department of Laboratory, The Hospital Affiliated to Medical College of Chinese People's Armed Police Force, Tianjin 300162, China
  • Received:2010-07-29 Revised:2010-09-20 Published:2010-11-25 Online:2010-11-25

PDF (PC)

被引次数

9

摘要： 目的总结脑脊液致病菌流行病学分布及耐药状况。方法对送检的脑脊液标本569份进行细菌鉴定及药敏测定。结果检出细菌阳性标本93份(16.3%)，其中革兰阳性菌52株，革兰阴性菌38株，真菌3株。万古霉素、利奈唑胺对革兰阳性球菌均有较高的抗菌活性；革兰阴性菌对常用药物头孢噻肟和头孢曲松的耐药率高，碳青霉烯类对革兰阴性菌有较好的抗菌活性。结论神经内外科患者颅内感染以革兰阳性球菌多见, 尤其是表皮葡萄球菌和金黄色葡萄球菌，以院内感染为主。

关键词: 脑脊液, 细菌培养, 耐药性

Abstract: ObjectiveTo analyze the distribution and antibiotic resistance of bacteria isolated from cerebrospinal fluid. Methods569 cerebrospinal fluild specimens were analyzed. ResultsPathogens were isolated from 93 specimens (16.3%), in which 52 were Gram positive bacteria and 38 were negative, 3 were fungi. All the Gram positive cocci were sensitive to vancomycin and linezolid, while the Gram negative bacteria were resistant to routine antibiotics such as cefotaxime and ceftriaxone, but sensitive to carbapenems. ConclusionThe prevailing pathogens in intracranial infection are Gram positive cocci, especially Staphylococcus epidermidis and Staphylococcus aureu.

Key words: cerebrospinal fluid, bacterial culture, drug resistance