《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (2): 172-173.

• 论文 • 上一篇    下一篇

吉兰-巴雷综合征早期的电生理发现

山磊1,2，Gastaldo Ernesto3，Enrico Granieri3，张通1,2   

  1. 1.首都医科大学康复医学院，北京市 100068；2.中国康复研究中心北京博爱医院，北京市 100068；3. Department of Neurology, S. Anna Hospital, Ferrara 44100, Italy。
  • 收稿日期:2009-07-14 修回日期:1900-01-01 出版日期:2010-02-25 发布日期:2010-02-25

Electrophysiological Findings at Early Stage of Guillain-Barré Syndrome

SHAN Lei, Gastaldo Ernesto, Enrico Granieri, et al.   

  1. Department of Neurorehabilitation, Beijing Charity Hosptial, 100068, China
  • Received:2009-07-14 Revised:1900-01-01 Published:2010-02-25 Online:2010-02-25

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摘要： 目的探讨吉兰-巴雷综合征发病早期不正常的神经电生理特点，从而了解其最频繁和敏感的共同神经传导模式。方法回顾性研究意大利费拉拉市S. Anna医院在2001～2007年中被诊断为吉兰-巴雷综合征并早期接受过神经电生理检查的33例患者。结果26(81%)例患者的F波不正常，11(34%)例患者的感觉动作电位波幅下降或消失，13例(41%)复合运动动作电位波幅下降，传导速度减慢、末端潜伏期延长和传导阻滞的患者相对比较少，分别为12.5%、25%和6%。仅有1例电生理检查均为正常。结论在吉兰-巴雷综合征患者的早期，F波测定较神经传导研究更加敏感，不正常的F波(如出现率下降、潜伏期延长)出现的最早也最常见。

关键词: 吉兰-巴雷综合征, 电生理, F波

Abstract: ObjectiveTo explore the characteristics of electrodiagnostic abnormalities at early stage of Guillain-Barré syndrome, and to determine which is the common most frequent and sensitive nerve conduction pattern. MethodsWe retrospectively reviewed the neurophysiological studies of all patients with Guillain-Barré Syndrome discharged from S. Anna Hospital in Ferrara, Italy from 2001 to 2007. Results26 patients (81%) had abnormal F wave. 11 patients (34%) had low amplitude or absent SAPs. 13 patients (41%) reduced compound muscle action potential, slowed conduction velocity, prolonged distal latency and conduction block were more fewer (respectively 12.5%, 25% and 6%). Only in 1 patient we had normal findings. ConclusionF wave is more sensitive than nerve conduction study at early stage of Guillain-Barré Syndrome. Abnormalities of F wave (frequency reduced, prolonged latency) are the most frequent and earlier test for Guillain-Barré Syndrome.

Key words: Guillain-Barré Syndrome, electrophysiology, F wave