《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (8): 704-706.

• 论文 • 上一篇    下一篇

星形胶质细胞与神经病理性疼痛

贾东林1，郭建荣2   

  1. 1.北京大学第三医院麻醉科，北京市 100191；2.宁波大学医学院附属李惠利医院麻醉科，浙江宁波市 315040
  • 收稿日期:2010-04-02 修回日期:1900-01-01 出版日期:2010-08-25 发布日期:2010-08-25
  • 通讯作者: 郭建荣

Advance in Astrocyte and Neuropathic Pain(rerview)

JIA Dong-lin, GUO Jian-rong

  

  1. Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, China
  • Received:2010-04-02 Revised:1900-01-01 Published:2010-08-25 Online:2010-08-25

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摘要： 星形胶质细胞是中枢神经系统分布最广、数量最多的细胞群体，有着复杂的信号转导系统，通过释放许多神经递质、神经营养因子和细胞因子参与疼痛信号的转导与调控。另外，星形胶质细胞还参与外周和中枢水平神经病理性疼痛的形成和发展。本文主要就星形胶质细胞起源、分类、功能、激活，参与疼痛调节机制，以及与神经病理性疼痛关系等进行文献综述。

关键词: 星形胶质细胞, 神经病理性疼痛, 综述

Abstract: Astrocyte is the most amount cell population of the central nervous system, which has complex signal transduction pathway. Astrocyte involves in many physiological actions and pathological processes. Further more, Astrocyte plays an important role in neuropathic pain generation and development at central nerve system level, or at peripheral level. This paper reviewed the evolution of astrocyte and neuropathic pain research in recent years.

Key words: astrocyte, neuropathic pain, review