《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (8): 713-715.

• 论文 • 上一篇    下一篇

玻璃酸钠注射配合体外冲击波治疗膝骨关节炎的临床观察

孟岚1a,樊啸1b   

  1. 1.首都医科大学附属北京天坛医院,a: 麻醉疼痛科;b: 医务处,北京市 100050
  • 收稿日期:2010-07-27 修回日期:1900-01-01 出版日期:2010-08-25 发布日期:2010-08-25

Combination of Intra-articular Injection of Hyaluronate and Extracorporeal Shock Wave Therapy on Knee Osteoarthritis

MENG Lan, FAN Xiao   

  1. Department of Anaesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2010-07-27 Revised:1900-01-01 Published:2010-08-25 Online:2010-08-25

摘要: 目的观察膝关节腔注射玻璃酸钠配合体外冲击波治疗膝骨关节炎的疗效。方法50例膝骨关节炎患者分为两组:研究组(关节腔注射玻璃酸钠配合体外冲击波治疗,n=22)和对照组(关节腔注射玻璃酸钠配合复方倍他米松痛点注射,n=28),关节腔注射治疗均为每周1次,5周为1个疗程。于治疗前及结束后1周记录安静时疼痛、运动时疼痛、疼痛消失的时间、应用糖皮质激素或体外冲击波治疗的次数、患者治疗后的疗效及副作用。结果治疗后两组患者症状均明显缓解,除治疗1周时对照组症状减轻程度较研究组明显(P<0.01)外,其余各时间段两组疗效均相当(P>0.05)。结论关节腔注射玻璃酸钠结合体外冲击波治疗膝骨关节炎安全有效。

关键词: 体外冲击波, 膝骨关节炎, 玻璃酸钠

Abstract: ObjectiveTo investigate the therapeutic efficacy and side effect of combination of intra-articular injection of hyaluronate and extracorporeal shock wave therapy(ESWT) on patients with knee osteoarthritis.Methods50 patients with knee osteoarthritis were treated by combination of intra-articular injection of hyaluronate and ESWT(study group, n=22) or combination of intra-articular injection of hyaluronate and pain-point injection of betamethasone(control group, n=28). The parameters included pain intensity (Numeric Rating Score, NRS) at rest and at exercise, pain relief rate, the time when pain disappeared and times of betamethasone administration or ESWT. The side effects were also evaluated.ResultsNRS decreased in the two groups after treatment,
while NRS was not different between the two groups(P>0.05) except 1 week after the treatment(P<0.01).ConclusionThe combination of intra-articular injection of hyaluronate and extracorporeal shock wave is a safe and effective treatment for knee osteoarthritis.

Key words: extracorporeal shock wave therapy(ESWT), knee osteoarthritis, hyaluronate