《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (9): 803-804.

• 论文 • 上一篇    下一篇

Toll样受体4信号转导通路在脑梗死后运动康复中的研究前景

马跃文，何曼   

  1. 中国医科大学附属第一医院康复医学科,辽宁沈阳市 110001。
  • 收稿日期:2010-07-19 修回日期:1900-01-01 出版日期:2010-09-25 发布日期:2010-09-25

Toll-like Receptor 4 Passway in Rehabilitation after Cerebral Infarction (review)

MA Yue-wen, HE Man   

  1. Department of Rehabilitation Medicine of the First Hospital of China Medical University, Shenyang 110001, Liaoning, China
  • Received:2010-07-19 Revised:1900-01-01 Published:2010-09-25 Online:2010-09-25

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摘要： 近年来发现，Toll样受体4（TLR4）信号转导通路在脑梗死后的炎症损伤中起重要作用，运动训练能降低TLR4的表达，减轻炎性损伤。我们可以考虑从TLR4信号转导方向深入探讨脑梗死后运动康复的作用机制。

关键词: 脑梗死, Toll样受体4, 运动, 康复, 综述

Abstract: Recently, Toll-like receptor 4 (TLR4) passway has been found to play an important role in the inflammation injury after cerebral infarction, and exercise seems to induce a downregulation of TLR4 expression in various tissues. It is possible that TLR4 plays an important role in the mechanism of rehabilitation after a cerebral infarction.

Key words: cerebral infarction, Toll-like receptor 4, exercise, rehabilitation, review